The presence of pharmaceutical residues in various environmental compartments is an
issue of increasing concern. The widespread occurrence of these compounds in water and …

BACKGROUND Although treatment-resistant hypertension (RH) is a serious burden on
population health, there exists uncertainty about its prevalence. Hence, the objectives of this …

Background—Despite a recent American Heart Association (AHA) consensus statement
emphasizing the importance of resistant hypertension, the incidence and prognosis of this …

Resistant hypertension represents a major clinical problem in everyday clinical practice, not
only for hypertension experts but for nephrologists, cardiologists, internists, and primary care …

In this review, we discuss the possible pathophysiological mechanisms and the role of
arterial stiffness as a biomarker, a blood pressure–independent predictor of cardiovascular …

The term “ultima ratio” has multiple, though related, meanings. The motto “ultima ratio
regum,” cast on the cannons of the French army of King Louis XIV, meant that war is the last …

Previous assessments of the prevalence of resistant hypertension (RH) in uncontrolled
blood pressure (BP) have ranged from 3% to 30%. Using real-world data, our aim was to …

Patients with resistant hypertension are at risk for poor outcomes. Medication adherence
and intensification improve blood pressure (BP) control; however, little is known about these …

Angiotensin II (Ang II) is associated with vascular hypertrophy, endothelial dysfunction and
activation of a number of inflammatory molecules, however the linear events involved in the …

Nonadherence is a common reason for treatment failure and treatment resistance. No matter
how it is defined, it is a major issue in the management of chronic illnesses. There are …