The glycocalyx, a thick layer of carbohydrates, surrounds the cell wall of most bacterial and
parasitic pathogens. Recognition of these unique glycans by the human immune system …

One could certainly highlight a conceptual resemblance between social interactions as the
basis of societies and civilizations and the ability of molecules to interact in a noncovalent …

Carbohydrates, which are ubiquitously distributed throughout the three domains of life, play
significant roles in a variety of vital biological processes. Access to unique and …

Carbohydrates possess a variety of distinct features with stereochemistry playing a
particularly important role in distinguishing their structure and function. Monosaccharide …

The composition of the Gram-positive cell wall is typically described as containing
peptidoglycan, proteins and essential secondary cell wall structures called teichoic acids …

Conspectus Carbohydrates are the most abundant biopolymers on earth and part of every
living creature. Glycans are essential as materials for nutrition and for information transfer in …

Glycoproteins are major players in the mucus protective barrier in the gastrointestinal and
other mucosal surfaces. In particular the mucus glycoproteins, or mucins, are responsible for …

The glycans displayed on mammalian cells can differ markedly from those on microbes.
Such differences could, in principle, be'read'by carbohydrate-binding proteins, or lectins. We …

Mass spectrometry is the primary analytical technique used to characterize the complex
oligosaccharides that decorate cell surfaces. Monosaccharide building blocks are often …

In this review, we document the evolution of common glycan structures in the eukaryotes,
and illustrate the considerable variety of oligosaccharides existing in these organisms. We …