Antioxidant nanotherapies for the treatment of inflammatory diseases

CW Li, LL Li, S Chen, JX Zhang, WL Lu - Frontiers in Bioengineering …, 2020 - frontiersin.org
Reactive oxygen species (ROS) are essential in regulating various physiological functions.
However, overproduction of ROS is implicated in the pathogenesis of various inflammatory …

Redox-active nanoparticles for inflammatory bowel disease

Q Ren, S Sun, XD Zhang - Nano Research, 2021 - Springer
Homeostasis of gut microbiota is extremely essential for maintaining nutrient metabolism
and regulating immunological function. The increasing evidence suggests that inflammatory …

A proresolving peptide nanotherapy for site‐specific treatment of inflammatory bowel disease by regulating proinflammatory microenvironment and gut microbiota

C Li, Y Zhao, J Cheng, J Guo, Q Zhang… - Advanced …, 2019 - Wiley Online Library
The incidence and prevalence of inflammatory bowel disease (IBD) increases steadily
worldwide. There is an urgent need for effective and safe IBD therapies. Accelerated …

[HTML][HTML] Lactoferrin-mediated macrophage targeting delivery and patchouli alcohol-based therapeutic strategy for inflammatory bowel diseases

Y Zhao, Y Yang, J Zhang, R Wang, B Cheng… - … Pharmaceutica Sinica B, 2020 - Elsevier
Inflammatory bowel diseases (IBD) are the incurable chronic recurrent gastrointestinal
disorders and currently lack in safe and effective drugs. In this study, patchouli alcohol, a …

Improving silymarin oral bioavailability using silica-installed redox nanoparticle to suppress inflammatory bowel disease

THT Nguyen, NT Trinh, HN Tran, HT Tran, PQ Le… - Journal of controlled …, 2021 - Elsevier
Chronic inflammatory diseases such as inflammatory bowel diseases (IBD), which are
strongly related to the overproduction of reactive oxygen species (ROS), have become more …

Hyaluronic acid modified oral drug delivery system with mucoadhesiveness and macrophage-targeting for colitis treatment

Y Zhang, R Ma, C You, X Leng, D Wang, S Deng… - Carbohydrate …, 2023 - Elsevier
Based on the biocompatibility and macrophage targeting of natural polysaccharides,
combined with the physiological and pathological characteristics of the gastrointestinal tract …

A Multi‐Bioactive Nanomicelle‐Based “One Stone for Multiple Birds” Strategy for Precision Therapy of Abdominal Aortic Aneurysms

W Lin, K Hu, C Li, W Pu, X Yan, H Chen… - Advanced …, 2022 - Wiley Online Library
Abdominal aortic aneurysm (AAA) remains a lethal aortic disease in the elderly. Currently,
no effective drugs can be clinically applied to prevent the development of AAA. Herein, a …

Hybrid hydrogel loaded with chlorhexidine⊂ β-CD-MSN composites as wound dressing

J Lin, T Shi, Y Wang, Z He, Z Mu, X Cai… - International Journal …, 2023 - Taylor & Francis
Background Much attention has been paid to sustained drug release and anti-infection in
wound management. Hydrogels, which are biocompatible materials, are promising tools for …

Targeting strategies of oral nano-delivery systems for treating inflammatory bowel disease

W Liu, Z Dong, K Liu, Y Lu, W Wu, J Qi… - International Journal of …, 2021 - Elsevier
Inflammatory bowel disease (IBD) is a chronic relapsing inflammatory disorder of
gastrointestinal tract with rising incidence. Established treatments of IBD are characterized …

Biomimetic and bioinspired strategies for oral drug delivery

X Hu, G Yang, S Chen, S Luo, J Zhang - Biomaterials science, 2020 - pubs.rsc.org
Oral drug delivery remains the most preferred approach due to its multiple advantages.
Recently there has been increasing interest in the development of advanced vehicles for …