High-throughput methods in the discovery and study of biomaterials and materiobiology
The complex interaction of cells with biomaterials (ie, materiobiology) plays an increasingly
pivotal role in the development of novel implants, biomedical devices, and tissue …
pivotal role in the development of novel implants, biomedical devices, and tissue …
Self-assembled monolayers of thiolates on metals as a form of nanotechnology
Nanoscience includes the study of objects and systems in which at least one dimension is 1-
100 nm. The objects studied in this range of sizes are larger than atoms and small …
100 nm. The objects studied in this range of sizes are larger than atoms and small …
Effect of wettability and surface functional groups on protein adsorption and cell adhesion using well-defined mixed self-assembled monolayers
Y Arima, H Iwata - Biomaterials, 2007 - Elsevier
Self-assembled monolayers (SAMs) of alkanethiols, which can provide flat and chemically
well-defined surfaces, were employed as model surfaces to understand cellular interaction …
well-defined surfaces, were employed as model surfaces to understand cellular interaction …
Adaptation of high-throughput screening in drug discovery—toxicological screening tests
P Szymański, M Markowicz… - International journal of …, 2011 - mdpi.com
High-throughput screening (HTS) is one of the newest techniques used in drug design and
may be applied in biological and chemical sciences. This method, due to utilization of …
may be applied in biological and chemical sciences. This method, due to utilization of …
The sweet and sour of cancer: glycans as novel therapeutic targets
A growing body of evidence supports crucial roles for glycans at various pathophysiological
steps of tumour progression. Glycans regulate tumour proliferation, invasion …
steps of tumour progression. Glycans regulate tumour proliferation, invasion …
Patterned superhydrophobic surfaces: toward a synthetic mimic of the Namib Desert beetle
The present study demonstrates a surface structure that mimics the water harvesting wing
surface of the Namib Desert beetle. Hydrophilic patterns on superhydrophobic surfaces …
surface of the Namib Desert beetle. Hydrophilic patterns on superhydrophobic surfaces …
A defined glycosaminoglycan-binding substratum for human pluripotent stem cells
To exploit the full potential of human pluripotent stem cells for regenerative medicine,
developmental biology and drug discovery, defined culture conditions are needed. Media of …
developmental biology and drug discovery, defined culture conditions are needed. Media of …
Materials control of the epigenetics underlying cell plasticity
The dynamic epigenetic landscape directs gene expression patterns that dictate cellular
form and function, and drive the assembly of cells into tissues. The high degree of plasticity …
form and function, and drive the assembly of cells into tissues. The high degree of plasticity …
High-throughput cellular microarray platforms: applications in drug discovery, toxicology and stem cell research
Cellular microarrays are powerful experimental tools for high-throughput screening of large
numbers of test samples. Miniaturization increases assay throughput while reducing reagent …
numbers of test samples. Miniaturization increases assay throughput while reducing reagent …
Diversity of phage-displayed libraries of peptides during panning and amplification
The amplification of phage-displayed libraries is an essential step in the selection of ligands
from these libraries. The amplification of libraries, however, decreases their diversity and …
from these libraries. The amplification of libraries, however, decreases their diversity and …