A pathological feature of Parkinson's disease (PD) is the progressive loss of dopaminergic
neurons and decreased dopamine (DA) content in the substantia nigra pars compacta in PD …

Parkinson's disease (PD) is the second most common neurodegenerative illness majorly
affecting the population between the ages of 55 to 65 years. Progressive dopaminergic …

Mitochondria are essential organelles for neuronal function and cell survival. Besides the
well-known bioenergetics, additional mitochondrial roles in calcium signaling, lipid …

Bioenergetic and mitochondrial dysfunction are common hallmarks of neurodegenerative
diseases. Decades of research describe how genetic and environmental factors initiate …

The goal of this study is to identify a signature of bioenergetic and functional markers in the
muscles of individuals with Parkinson's disease (PD). Quantitative physiological properties …

A growing amount of evidence has indicated contributions of variants in causative genes of
Parkinson's disease (PD) to the development of sleep disturbance in PD and prodromal PD …

Despite the discovery of numerous molecules and pathologies, the pathophysiology of
various neurodegenerative diseases remains unknown. Genetics participates in the …

Growing neurological diseases pose difficult challenges for modern medicine to diagnose
and manage them effectively. Many neurological disorders mainly occur due to genetic …

In severe cases, Parkinson's disease causes uncontrolled movements known as motor
symptoms such as dystonia, rigidity, bradykinesia, and tremors. Parkinson's disease also …

Parkinson's disease (PD) is the second most prevalent neurodegenerative movement
disorder worldwide, which is primarily characterized by motor impairments. Even though …