Biofilm dispersion

KP Rumbaugh, K Sauer - Nature Reviews Microbiology, 2020 - nature.com
The formation of microbial biofilms enables single planktonic cells to assume a multicellular
mode of growth. During dispersion, the final step of the biofilm life cycle, single cells egress …

[HTML][HTML] Challenges of intervention, treatment, and antibiotic resistance of biofilm-forming microorganisms

G Gebreyohannes, A Nyerere, C Bii, DB Sbhatu - Heliyon, 2019 - cell.com
Background Biofilms are multicellular communities of microorganisms held together by a self-
produced extracellular matrix. The ability of microbes to form biofilm is a universal …

[HTML][HTML] Treatment of Pseudomonas aeruginosa infectious biofilms: Challenges and strategies

R Yin, J Cheng, J Wang, P Li, J Lin - Frontiers in Microbiology, 2022 - frontiersin.org
Pseudomonas aeruginosa, a Gram-negative bacterium, is one of the major pathogens
implicated in human opportunistic infection and a common cause of clinically persistent …

Fatty acids as antibiofilm and antivirulence agents

P Kumar, JH Lee, H Beyenal, J Lee - Trends in microbiology, 2020 - cell.com
Fatty acids (FAs) have emerged as a potential alternative to conventional antibiotics. Since
many microbes respond differently to a variety of natural and synthetic FAs, substantial …

[HTML][HTML] Approaches to dispersing medical biofilms

D Fleming, KP Rumbaugh - Microorganisms, 2017 - mdpi.com
Biofilm-associated infections pose a complex problem to the medical community, in that
residence within the protection of a biofilm affords pathogens greatly increased tolerances to …

[HTML][HTML] Targeting biofilms therapy: current research strategies and development hurdles

Y Jiang, M Geng, L Bai - Microorganisms, 2020 - mdpi.com
Biofilms are aggregate of microorganisms in which cells are frequently embedded within a
self-produced matrix of extracellular polymeric substance (EPS) and adhere to each other …

[HTML][HTML] Anti-biofilm activity as a health issue

S Miquel, R Lagrafeuille, B Souweine… - Frontiers in …, 2016 - frontiersin.org
The formation and persistence of surface-attached microbial communities, known as
biofilms, are responsible for 75% of human microbial infections (National Institutes of …

[HTML][HTML] The DSF family of cell–cell signals: an expanding class of bacterial virulence regulators

RP Ryan, S An, JH Allan, Y McCarthy, JM Dow - PLoS pathogens, 2015 - journals.plos.org
Many pathogenic bacteria use cell–cell signaling systems involving the synthesis and
perception of diffusible signal molecules to control virulence as a response to cell density or …

[HTML][HTML] Factors mediating Acinetobacter baumannii biofilm formation: Opportunities for developing therapeutics

K Upmanyu, QMR Haq, R Singh - Current Research in Microbial Sciences, 2022 - Elsevier
Acinetobacter baumannii has notably become a superbug due to its mounting risk of
infection and escalating rates of antimicrobial resistance, including colistin, the last-resort …

Inhibition of polymicrobial biofilm formation by saw palmetto oil, lauric acid and myristic acid

YG Kim, JH Lee, S Park, S Kim, J Lee - Microbial biotechnology, 2022 - Wiley Online Library
Biofilms are communities of bacteria, fungi or yeasts that form on diverse biotic or abiotic
surfaces, and play important roles in pathogenesis and drug resistance. A generic saw …