Adipose tissue is the largest endocrine organ and an accepted contributor to overall energy
homeostasis. There is strong evidence linking increased adiposity to the development of 13 …

Obesity causes chronic low-grade inflammation and leads to changes in the immune
landscape of multiple organ systems. Given the link between chronic inflammatory …

Immune checkpoint blockade (ICB) as a powerful immunotherapy has transformed cancer
treatment. The application of ICB to genitourinary malignancies has generated substantial …

Neutrophils have emerged as important players in the tumor microenvironment, largely
attributed to their plasticity and heterogeneity. Evidence accumulated thus far indicates that …

Renal cell carcinoma (RCC) is one of the most common urologic malignancies with the
highest mortality rates worldwide. However, relevant mouse models that recapitulated the …

Introduction Neutrophils play a complex and important role in the immunopathology of TB.
Data suggest they are protective during early infection but become a main driver of …

Obesity is a chronic disease caused by the accumulation of excessive adipose tissue. This
disorder is characterized by chronic low‑grade inflammation, which promotes the release of …

Abstract This 14‐color, 13‐antibody optimized multicolor immunofluorescence panel (OMIP)
was designed for deep profiling of neutrophil subsets in various types of human samples to …

Cancer is one of the deadliest diseases with a cure far from being found. Despite the
extraordinary advances in the therapy approaches, only a few patients respond to …

Obesity is a chronic disease caused by the accumulation of excessive adipose tissue. This
disorder is characterized by chronic low-grade inflammation, which promotes the release of …