Regulation of sexual commitment and gametocytogenesis in malaria parasites

GA Josling, KC Williamson… - Annual review of …, 2018 - annualreviews.org
Sexual differentiation of malaria parasites from the asexual blood stage into gametocytes is
an essential part of the life cycle, as gametocytes are the form that is taken up by the …

ApiAP2 transcription factors in apicomplexan parasites

MD Jeninga, JE Quinn, M Petter - Pathogens, 2019 - mdpi.com
Apicomplexan parasites are protozoan organisms that are characterised by complex life
cycles and they include medically important species, such as the malaria parasite …

Babesia duncani multi-omics identifies virulence factors and drug targets

P Singh, S Lonardi, Q Liang, P Vydyam… - Nature …, 2023 - nature.com
Babesiosis is a malaria-like disease in humans and animals that is caused by Babesia
species, which are tick-transmitted apicomplexan pathogens. Babesia duncani causes …

Novel insights into the role of long non-coding RNA in the human malaria parasite, Plasmodium falciparum

G Batugedara, XM Lu, B Hristov, S Abel… - Nature …, 2023 - nature.com
The complex life cycle of Plasmodium falciparum requires coordinated gene expression
regulation to allow host cell invasion, transmission, and immune evasion. Increasing …

Variable microtubule architecture in the malaria parasite

JL Ferreira, V Pražák, D Vasishtan, M Siggel… - Nature …, 2023 - nature.com
Microtubules are a ubiquitous eukaryotic cytoskeletal element typically consisting of 13
protofilaments arranged in a hollow cylinder. This arrangement is considered the canonical …

[HTML][HTML] Long noncoding RNA MEG3 suppresses glioma cell proliferation, migration, and invasion by acting as a competing endogenous RNA of miR-19a

N Qin, GF Tong, LW Sun, XL Xu - Oncology research, 2017 - ncbi.nlm.nih.gov
Glioma, with varying malignancy grades and histological subtypes, is the most common
primary brain tumor in adults. Long noncoding RNAs (lncRNAs) are non-protein-coding …

[HTML][HTML] The dynamic roles of the inner membrane complex in the multiple stages of the malaria parasite

JL Ferreira, D Heincke, JS Wichers, B Liffner… - Frontiers in Cellular …, 2021 - frontiersin.org
Apicomplexan parasites, such as human malaria parasites, have complex lifecycles
encompassing multiple and diverse environmental niches. Invading, replicating, and …

[PDF][PDF] Comparative heterochromatin profiling reveals conserved and unique epigenome signatures linked to adaptation and development of malaria parasites

SA Fraschka, M Filarsky, R Hoo, I Niederwieser… - Cell host & …, 2018 - cell.com
Heterochromatin-dependent gene silencing is central to the adaptation and survival of
Plasmodium falciparum malaria parasites, allowing clonally variant gene expression during …

[PDF][PDF] A specific PfEMP1 is expressed in P. falciparum sporozoites and plays a role in hepatocyte infection

G Zanghì, SS Vembar, S Baumgarten, S Ding… - Cell reports, 2018 - cell.com
Heterochromatin plays a central role in the process of immune evasion, pathogenesis, and
transmission of the malaria parasite Plasmodium falciparum during blood stage infection …

Epigenetic Regulation and Chromatin Remodeling in Malaria Parasites

T Hollin, Z Chahine, KG Le Roch - Annual Review of …, 2023 - annualreviews.org
Plasmodium falciparum, the human malaria parasite, infects two hosts and various cell
types, inducing distinct morphological and physiological changes in the parasite in response …