Primary immunodeficiencies affecting the function of neutrophils and other phagocytic
leukocytes are notable for an increased susceptibility to bacterial and fungal infections as a …

Background Thalidomide is the most teratogenic human medicine ever marketed and was
associated with birth defects in approximately 10,000 children in the 1960s. The …

Cutaneous lupus erythematosus (CLE) is an inflammatory, autoimmune disease
encompassing a broad spectrum of subtypes including acute, subacute, chronic and …

Oral lichen planus (OLP) is a chronic inflammatory disorder with a multifactorial
etiopathogenesis. Immune dysregulation plays a critical role in the development and …

Immune deficiencies resulting from inherited defects in neutrophil function have revealed
important features of the innate immune response. Although sharing an increased …

Acute kidney injury (AKI) is an important clinical complication of rhabdomyolysis. The
inflammatory processes are involved in the pathogenesis of AKI induced by rhabdomyolysis …

Abstract Purpose of Review This manuscript aims to review the cutting-edge developments
regarding to the diagnosis, management, and prevention of leprosy in children. Recent …

Pruritus is a common and often times difficult to treat symptom in many dermatologic and
systemic diseases. For pruritus with an inflammatory or autoimmune origin, therapies such …

Background: Thalidomide is an immunomodulatory drug used in the experimental treatment
of refractory Crohn disease and ulcerative colitis. We aimed to review the existing evidence …

Bullous diseases are uncommon in children; however, as they have the potential to affect
quality of life, occasionally have long-term side effects in the setting of scarring processes …