[PDF][PDF] Phytochemicals in antidiabetic drug discovery

R Singh, T Arif, I Khan, P Sharma - J. Biomed. Ther. Sci, 2014 - academia.edu
Management of diabetes mellitus is a challenge for clinicians. Uncontrolled hyperglycemia
increases the risk of microvascular and macrovascular complications, damaging the body …

[HTML][HTML] Aqueous-Methanol Extracts of Orange-Fleshed Sweet Potato (Ipomoea batatas) Ameliorate Oxidative Stress and Modulate Type 2 Diabetes Associated …

TB Ayeleso, K Ramachela, E Mukwevho - Molecules, 2018 - mdpi.com
Edible plants such as sweet potato are sources of natural antioxidants that can be exploited
in the management and treatment of insulin resistance. This present study investigated the …

[HTML][HTML] Lactate-Fortified Puerariae Radix Fermented by Bifidobacterium breve Improved Diet-Induced Metabolic Dysregulation via Alteration of Gut Microbial …

Y Choi, S Bose, NR Shin, EJ Song, YD Nam, H Kim - Nutrients, 2020 - mdpi.com
Background: Puerariae Radix (PR), the dried root of Pueraria lobata, is reported to possess
therapeutic efficacies against various diseases including obesity, diabetes, and …

Reduced gene expression of sirtuins and active AMPK levels in children and adolescents with obesity and insulin resistance

ZA Sadeghabadi, M Nourbakhsh, P Pasalar… - Obesity research & …, 2018 - Elsevier
Background Sirtuins, including SIRT1 and SIRT2, are longevity-associated deacetylase
enzymes that modulate metabolic homeostasis in response to the cellular energy state …

[HTML][HTML] Association between miR-138-5p, miR-132-3p, SIRT1, STAT3, and CD36 and atherogenic indices in blood mononuclear cells from patients with …

S Ehsani, M Mard‑Soltani, F Ahmadpour… - Egyptian Journal of …, 2023 - Springer
Backgrounds Developed countries have a high mortality rate from atherosclerosis and are
frequently linked to inflammation and other blood lipid disorders. MicroRNA expression can …

[PDF][PDF] Regulatory and metabolic interactions of carbohydrates and lipids in diabetes and obesity

C Chukwuma Sr - J Biotech Res, 2019 - academia.edu
This paper attempts to review available pertinent scientific and medical literature that the
current global epidemic of obesity and diabetes has increased simultaneously or …

[HTML][HTML] Evaluation of free radical scavenging capacity of methoxy containing-hybrids of thiosemicarbazone-triazole and their influence on glucose transport

AO Ayeleso, JS Joseph, OO Oguntibeju… - BMC Pharmacology and …, 2018 - Springer
Background Diabetes mellitus is a metabolic disease in which the body is unable to produce
insulin or respond to insulin production, consequently leading to abnormal metabolism of …

[PDF][PDF] Pathophysiologic functions of carbohydrate-lipid interactions: Ascertainment in obesity, diabetes and SARS-CoV-2/COVID-19

C Chukwuma Sr - J Biotechnol Its Applications, 2022 - academia.edu
The extant COVID-19 pandemic has resulted in an expansive mortality due to the SARS-
CoV-2. The SARS-CoV-2 is encompassed by a lipid bilayer that enhances fusion of the viral …

Role of phytochemicals in Allium sativum on obesity: a review

AE Adepoju, G Joseph, SO Babarinde… - … Properties of Medicinal …, 2023 - taylorfrancis.com
The imbalance of energy metabolism over the last several decades has been a challenge
for metabolic disorders. Obesity is caused by uncontrolled energy regulation, resulting in fat …

[PDF][PDF] Etiopathophysiological functions of carbohydrate-lipid interactions associated with obesity, diabetes and COVID-19

C Chukwuma Sr - Diabetes & Obesity International Journal, 2022 - researchgate.net
The extant COVID-19 pandemic has resulted in an expansive mortality due to the SARS-
COV-2. The SARS-COV-2 is encompassed by a lipid bilayer that enhances fusion of the viral …