Yohimbine ameliorates liver inflammation and fibrosis by regulating oxidative stress and Wnt/β-catenin pathway

N Sharma, R Sistla, SB Andugulapati - Phytomedicine, 2024 - Elsevier
Background and purpose Chronic liver injury, caused by various aetiologies, causes
recurrent tissue damage, culminating in decreased liver regenerative ability and resulting in …

Estimation of genetic diversity and population genetic structure in Gymnema sylvestre (Retz.) R. Br. ex Schult. populations using DAMD and ISSR markers

K Vaishnav, V Tiwari, A Durgapal, B Meena… - Journal of Genetic …, 2023 - Elsevier
Abstract Background Gymnema sylvestre (Retz.) R. Br. ex Schult. is a well-known medicinal
plant against diabetes in India. There is as such no organized cultivation in India, and the …

[HTML][HTML] Renal mitochondrial restoration by gymnemic acid in gentamicin-mediated experimental nephrotoxicity: evidence from serum, kidney and histopathological …

S Gumbar, S Bhardwaj, S Mehan, Z Khan… - Frontiers in …, 2023 - frontiersin.org
Background: Nephrotoxicity refers to the toxigenic impact of compounds and medications on
kidney function. There are a variety of drug formulations, and some medicines that may …

[HTML][HTML] Rosavin alleviates LPS-induced acute lung injure by modulating the TLR-4/NF-κB/MAPK singnaling pathways

QH Liu, K Zhang, SS Feng, LJ Zhang, SY Li… - International Journal of …, 2024 - mdpi.com
Acute lung injury (ALI) is a serious inflammatory disease with high morbidity and mortality.
Rosavin is an anti-inflammatory and antioxidant phenylpropanoid and glucoside, which is …

[HTML][HTML] Gymnema sylvestre extract improves PCOS by altering the YAP1 protein in the mouse ovary via mitochondrial changes

A Jangam, RSS Kotipalli, SS Patnaik, B Kasireddy… - Phytomedicine Plus, 2024 - Elsevier
Abstract Background Gymnema sylvestre (Retz.) R. Br. ex Sm. is a medicinal herb used in
Ayurvedic medicine to treat diabetes. Through promoting obesity and lowering insulin …

Vistusertib improves pulmonary inflammation and fibrosis by modulating inflammatory/oxidative stress mediators via suppressing the mTOR signalling

TB Shaikh, Y Chandra, SB Andugulapati… - Inflammation Research, 2024 - Springer
Introduction Inflammation and oxidative stress are key factors in the development of
pulmonary fibrosis (PF) by promoting the differentiation of fibroblasts through modulating …

[HTML][HTML] Comparative Effects of Gymnema sylvestre and Berberine on Adipokines, Body Composition, and Metabolic Parameters in Obese Patients: A Randomized …

C Bandala, J Carro-Rodríguez, N Cárdenas-Rodríguez… - Nutrients, 2024 - mdpi.com
Gymnema sylvestre (GS) and berberine (BBR) are natural products that have demonstrated
therapeutic potential for the management of obesity and its comorbidities, as effective and …

[HTML][HTML] Valsartan attenuates LPS-induced ALI by modulating NF-κB and MAPK pathways

M Zhou, L Meng, Q He, C Ren, C Li - Frontiers in Pharmacology, 2024 - frontiersin.org
Background: Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a
common respiratory disease characterized by persistent hypoxemia and an uncontrolled …

Glucosyltriazole amphiphile treatment attenuates breast cancer by modulating the AMPK signaling

NK Chouhan, A Eedara, MN Talati… - Drug Development …, 2024 - Wiley Online Library
Breast cancer is the second most frequent cancer among women. Out of various subtypes,
triple‐negative breast cancers (TNBCs) account for 15% of breast cancers and exhibit more …

Phytochemical profiling, human insulin stability and alpha glucosidase inhibition of Gymnema latifolium leaves aqueous extract: Exploring through experimental and …

S Ismail, TI Chandel, J Ramakrishnan, RH Khan… - … Biology and Chemistry, 2023 - Elsevier
Abstract Diabetes mellitus Type 2 (DM2T) is a rapidly expanding metabolic endocrine
disorder worldwide. It is caused due to inadequate insulin secretion by pancreatic beta cells …