Signaling pathways involved in ischemic stroke: molecular mechanisms and therapeutic interventions
C Qin, S Yang, YH Chu, H Zhang, XW Pang… - Signal transduction and …, 2022 - nature.com
Ischemic stroke is caused primarily by an interruption in cerebral blood flow, which induces
severe neural injuries, and is one of the leading causes of death and disability worldwide …
severe neural injuries, and is one of the leading causes of death and disability worldwide …
Neuroinflammation: friend and foe for ischemic stroke
RL Jayaraj, S Azimullah, R Beiram, FY Jalal… - Journal of …, 2019 - Springer
Stroke, the third leading cause of death and disability worldwide, is undergoing a change in
perspective with the emergence of new ideas on neurodegeneration. The concept that …
perspective with the emergence of new ideas on neurodegeneration. The concept that …
Nrf2–ARE pathway: an emerging target against oxidative stress and neuroinflammation in neurodegenerative diseases
Neurodegenerative diseases (NDDs) are predicted to be the biggest health concern in this
century and the second leading cause of death by 2050. The main risk factor of these …
century and the second leading cause of death by 2050. The main risk factor of these …
Neuroimmune mechanisms and therapies mediating post-ischaemic brain injury and repair
T Shichita, H Ooboshi, A Yoshimura - Nature Reviews Neuroscience, 2023 - nature.com
The nervous and immune systems control whole-body homeostasis and respond to various
types of tissue injury, including stroke, in a coordinated manner. Cerebral ischaemia and …
types of tissue injury, including stroke, in a coordinated manner. Cerebral ischaemia and …
Interleukin-6: a novel target for cardio-cerebrovascular diseases
JH Su, MY Luo, N Liang, SX Gong, W Chen… - Frontiers in …, 2021 - frontiersin.org
Cardio-Cerebrovascular Disease is a collective term for cardiovascular disease and
cerebrovascular disease, being a serious threat to human health. A growing number of …
cerebrovascular disease, being a serious threat to human health. A growing number of …
Hollow prussian blue nanozymes drive neuroprotection against ischemic stroke via attenuating oxidative stress, counteracting inflammation, and suppressing cell …
K Zhang, M Tu, W Gao, X Cai, F Song, Z Chen… - Nano …, 2019 - ACS Publications
Ischemic stroke is a devastating disease and one of the leading causes of mortality
worldwide. Overproduction of reactive oxygen and nitrogen species (RONS) following …
worldwide. Overproduction of reactive oxygen and nitrogen species (RONS) following …
Inflammatory mechanisms in ischemic stroke: role of inflammatory cells
R Jin, G Yang, G Li - Journal of leukocyte biology, 2010 - academic.oup.com
Review on the time-dependent recruitment of inflammatory cells and unanswered questions
regarding inflammatory cells in the pathophysiology of ischemic stroke. Inflammation plays …
regarding inflammatory cells in the pathophysiology of ischemic stroke. Inflammation plays …
Role of inflammation and its mediators in acute ischemic stroke
Inflammation plays an important role in the pathogenesis of ischemic stroke and other forms
of ischemic brain injury. Increasing evidence suggests that inflammatory response is a …
of ischemic brain injury. Increasing evidence suggests that inflammatory response is a …
Inflammatory mechanisms in ischemic stroke: therapeutic approaches
SE Lakhan, A Kirchgessner, M Hofer - Journal of translational medicine, 2009 - Springer
Acute ischemic stroke is the third leading cause of death in industrialized countries and the
most frequent cause of permanent disability in adults worldwide. Despite advances in the …
most frequent cause of permanent disability in adults worldwide. Despite advances in the …
The importance of early brain injury after subarachnoid hemorrhage
Aneurysmal subarachnoid hemorrhage (aSAH) is a medical emergency that accounts for
5% of all stroke cases. Individuals affected are typically in the prime of their lives (mean age …
5% of all stroke cases. Individuals affected are typically in the prime of their lives (mean age …