Peptide nucleic acid or PNA is a synthetic DNA mimic that contains a sequence of
nucleobases attached to a peptide-like backbone derived from N-2-aminoethylglycine. The …

Conformational preferences of the pyrrolidine ring in nucleotide analogs 7–14 were
investigated by means of NMR and molecular modeling. The effect of the relative …

This report describes the synthesis of C-rich sequence, cytosine pentamer, of aep-PNA and
its biophysical studies for the formation of hybrid DNA: aep-PNAi-motif structure with DNA …

We have analyzed the J values of 2, 5‐disubstituted and 2‐monosubstituted N‐
acylpyrrolidines in all the eight d‐aminohexitol and the four d‐aminopentitol series. The N …

In this chapter, which is devoted to applications of spin–spin couplings, the literature
published between June 2012 and May 2013 has been reviewed. The data included has …

This chapter highlights the most recent advances in the synthesis of monomers for being
incorporated into constrained peptide nucleic acid (PNA) analogues with a special focus on …

Magnetic interactions between nuclei are one of the most important phenomena in nuclear
magnetic resonance (NMR) spectroscopy. Both direct (D) and indirect (J) spin-spin …

The report covers and introduces studies on the application of nuclear shielding, related
NMR chemical shifts and NMR lineshapes, which were made in the world from 1 June 2010 …