[HTML][HTML] The Nuclear Factor Kappa B (NF-kB) signaling in cancer development and immune diseases
The nuclear factor kappa B (NF-êB) family of transcription factors plays an essential role as
stressors in the cellular environment, and controls the expression of important regulatory …
stressors in the cellular environment, and controls the expression of important regulatory …
Signaling via the NFκB system
The nuclear factor kappa B (NFκB) family of transcription factors is a key regulator of immune
development, immune responses, inflammation, and cancer. The NFκB signaling system …
development, immune responses, inflammation, and cancer. The NFκB signaling system …
NFKB1: a suppressor of inflammation, ageing and cancer
T Cartwright, ND Perkins, C L. Wilson - The FEBS journal, 2016 - Wiley Online Library
The pleiotropic consequences of nuclear factor of kappa light polypeptide gene enhancer in
B‐cells (NF‐κB) pathway activation result from the combinatorial effects of the five subunits …
B‐cells (NF‐κB) pathway activation result from the combinatorial effects of the five subunits …
Genome reading by the NF-κB transcription factors
The NF-κB family of dimeric transcription factors regulates transcription by selectively
binding to DNA response elements present within promoters or enhancers of target genes …
binding to DNA response elements present within promoters or enhancers of target genes …
The NF-κB multidimer system model: A knowledge base to explore diverse biological contexts
The nuclear factor κB (NF-κB) system is critical for various biological functions in numerous
cell types, including the inflammatory response, cell proliferation, survival, differentiation …
cell types, including the inflammatory response, cell proliferation, survival, differentiation …
An epithelial Nfkb2 pathway exacerbates intestinal inflammation by supplementing latent RelA dimers to the canonical NF-κB module
Aberrant inflammation, such as that associated with inflammatory bowel disease (IBD), is
fueled by the inordinate activity of RelA/NF-κB factors. As such, the canonical NF-κB module …
fueled by the inordinate activity of RelA/NF-κB factors. As such, the canonical NF-κB module …
Inflammation and NF-κB signaling in prostate cancer: Mechanisms and clinical implications
J Staal, R Beyaert - Cells, 2018 - mdpi.com
Prostate cancer is a highly prevalent form of cancer that is usually slow-developing and
benign. Due to its high prevalence, it is, however, still the second most common cause of …
benign. Due to its high prevalence, it is, however, still the second most common cause of …
New insights into NF-κB signaling in innate immunity: focus on immunometabolic crosstalks
D Iacobazzi, P Convertini, S Todisco, A Santarsiero… - Biology, 2023 - mdpi.com
Simple Summary NF-κB transcription factors are leading modulators of innate immunity.
Recent investigations reveal their interplay with energetic metabolism as a central task of …
Recent investigations reveal their interplay with energetic metabolism as a central task of …
The NF-κB transcriptional network is a high-dose vitamin C-targetable vulnerability in breast cancer
Breast cancer (BC) is the most common cancer type among women with a distinct clinical
presentation, but the survival rate remains moderate despite advances in multimodal …
presentation, but the survival rate remains moderate despite advances in multimodal …
Flow-Induced Shear Stress Primes NLRP3 Inflammasome Activation in Macrophages via Piezo1
A Fish, A Kulkarni - ACS Applied Materials & Interfaces, 2024 - ACS Publications
The NLRP3 inflammasome is a crucial component of the innate immune system, playing a
pivotal role in initiating and regulating the body's inflammatory response to various …
pivotal role in initiating and regulating the body's inflammatory response to various …