Hierarchically oriented organization in supramolecular peptide crystals
Hierarchical self-assembly and crystallization with long-range ordered spatial arrangement
is ubiquitous in nature and plays an essential role in the regulation of structures and …
is ubiquitous in nature and plays an essential role in the regulation of structures and …
Modeling semiflexible polymer networks
CP Broedersz, FC MacKintosh - Reviews of Modern Physics, 2014 - APS
This is an overview of theoretical approaches to semiflexible polymers and their networks.
Such semiflexible polymers have large bending rigidities that can compete with the entropic …
Such semiflexible polymers have large bending rigidities that can compete with the entropic …
Actin bundles dynamics and architecture
S Rajan, DS Kudryashov, E Reisler - Biomolecules, 2023 - mdpi.com
Cells use the actin cytoskeleton for many of their functions, including their division,
adhesion, mechanosensing, endo-and phagocytosis, migration, and invasion. Actin bundles …
adhesion, mechanosensing, endo-and phagocytosis, migration, and invasion. Actin bundles …
Structure and dynamics of cross-linked actin networks
O Lieleg, MMAE Claessens, AR Bausch - Soft Matter, 2010 - pubs.rsc.org
The actin cytoskeleton, a network of protein-polymers, is responsible for the mechanical
stability of cells. This biopolymer network is also crucial for processes that require spatial …
stability of cells. This biopolymer network is also crucial for processes that require spatial …
Synaptopodin regulates the actin-bundling activity of α-actinin in an isoform-specific manner
K Asanuma, K Kim, J Oh, L Giardino… - The Journal of …, 2005 - Am Soc Clin Investig
Synaptopodin is the founding member of a novel class of proline-rich actin-associated
proteins highly expressed in telencephalic dendrites and renal podocytes. Synaptopodin …
proteins highly expressed in telencephalic dendrites and renal podocytes. Synaptopodin …
Extracellular barriers in respiratory gene therapy
N Sanders, C Rudolph, K Braeckmans… - Advanced drug delivery …, 2009 - Elsevier
Respiratory gene therapy has been considered for the treatment of a broad range of
pulmonary disorders. However, respiratory secretions form an important barrier towards the …
pulmonary disorders. However, respiratory secretions form an important barrier towards the …
Fascin-and α-actinin-bundled networks contain intrinsic structural features that drive protein sorting
Cells assemble and maintain functionally distinct actin cytoskeleton networks with various
actin filament organizations and dynamics through the coordinated action of different sets of …
actin filament organizations and dynamics through the coordinated action of different sets of …
Spontaneous and x-ray–triggered crystallization at long range in self-assembling filament networks
We report here crystallization at long range in networks of like-charge supramolecular
peptide filaments mediated by repulsive forces. The crystallization is spontaneous beyond a …
peptide filaments mediated by repulsive forces. The crystallization is spontaneous beyond a …
Disease-associated mutant α-actinin-4 reveals a mechanism for regulating its F-actin-binding affinity
A Weins, JS Schlondorff, F Nakamura… - Proceedings of the …, 2007 - National Acad Sciences
α-Actinin-4 is a widely expressed protein that employs an actin-binding site with two
calponin homology domains to crosslink actin filaments (F-actin) in a Ca2+-sensitive manner …
calponin homology domains to crosslink actin filaments (F-actin) in a Ca2+-sensitive manner …
Actin cross-link assembly and disassembly mechanics for α-actinin and fascin
DS Courson, RS Rock - Journal of Biological Chemistry, 2010 - ASBMB
Self-assembly of complex structures is commonplace in biology but often poorly understood.
In the case of the actin cytoskeleton, a great deal is known about the components that …
In the case of the actin cytoskeleton, a great deal is known about the components that …