Molecular mechanisms of the efficacy of cold atmospheric pressure plasma (CAP) in cancer treatment

ML Semmler, S Bekeschus, M Schäfer, T Bernhardt… - Cancers, 2020 - mdpi.com
Recently, the potential use of cold atmospheric pressure plasma (CAP) in cancer treatment
has gained increasing interest. Especially the enhanced selective killing of tumor cells …

[HTML][HTML] Medical gas plasma technology: Roadmap on cancer treatment and immunotherapy

S Bekeschus - Redox Biology, 2023 - Elsevier
Despite continuous therapeutic progress, cancer remains an often fatal disease. In the early
2010s, first evidence in rodent models suggested promising antitumor action of gas plasma …

Subcellular mechanism of microbial inactivation during water disinfection by cold atmospheric-pressure plasma

H Xu, Y Zhu, M Du, Y Wang, S Ju, R Ma, Z Jiao - Water Research, 2021 - Elsevier
Although the identification of effective reactive oxygen species (ROS) generated by plasma
has been extensively studied, yet the subcellular mechanism of microbial inactivation has …

Low-temperature plasma for biology, hygiene, and medicine: Perspective and roadmap

M Laroussi, S Bekeschus, M Keidar… - … on Radiation and …, 2021 - ieeexplore.ieee.org
Plasma, the fourth and most pervasive state of matter in the visible universe, is a fascinating
medium that is connected to the beginning of our universe itself. Man-made plasmas are at …

Diffusion and transport of reactive species across cell membranes

MN Möller, E Cuevasanta, F Orrico, AC Lopez… - Bioactive lipids in health …, 2019 - Springer
This chapter includes an overview of the structure of cell membranes and a review of the
permeability of membranes to biologically relevant oxygen and nitrogen reactive species …

Unraveling the transport properties of RONS across nitro-oxidized membranes

D Abduvokhidov, M Yusupov, A Shahzad, P Attri… - Biomolecules, 2023 - mdpi.com
The potential of cold atmospheric plasma (CAP) in biomedical applications has received
significant interest, due to its ability to generate reactive oxygen and nitrogen species …

Molecular dynamics simulations of the effects of lipid oxidation on the permeability of cell membranes

D Wiczew, N Szulc, M Tarek - Bioelectrochemistry, 2021 - Elsevier
The formation of transient pores in their membranes is a well-known mechanism of
permeabilization of cells exposed to high-intensity electric pulses. However, the formation of …

Effects of nitro-oxidative stress on biomolecules: part 1—non-reactive molecular dynamics simulations

M Ghasemitarei, T Ghorbi, M Yusupov, Y Zhang… - Biomolecules, 2023 - mdpi.com
Plasma medicine, or the biomedical application of cold atmospheric plasma (CAP), is an
expanding field within plasma research. CAP has demonstrated remarkable versatility in …

The permeability of human red blood cell membranes to hydrogen peroxide is independent of aquaporins

F Orrico, AC Lopez, D Saliwonczyk, C Acosta… - Journal of Biological …, 2022 - ASBMB
Hydrogen peroxide (H 2 O 2) not only is an oxidant but also is an important signaling
molecule in vascular biology, mediating several physiological functions. Red blood cells …

Molecular dynamics simulation of the transmembrane transport process of reactive species under the synergistic effect of plasma oxidation and an electric field

Y Cui, T Zhao, H Wang, X Wang, D Wang… - Free Radical Biology and …, 2023 - Elsevier
Cold atmospheric pressure plasma (CAP)-assisted cancer therapy has become a popular
topic in plasma biomedical research. Membrane lipid oxidation and local electric fields are …