Advances in PET imaging of cancer

J Schwenck, D Sonanini, JM Cotton… - Nature Reviews …, 2023 - nature.com
Molecular imaging has experienced enormous advancements in the areas of imaging
technology, imaging probe and contrast development, and data quality, as well as machine …

ImmunoPET: concept, design, and applications

W Wei, ZT Rosenkrans, J Liu, G Huang, QY Luo… - Chemical …, 2020 - ACS Publications
Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

Relevance of immune cell and tumor microenvironment imaging in the new era of immunotherapy

F Galli, JV Aguilera, B Palermo, SN Markovic… - Journal of experimental …, 2020 - Springer
Tumor-infiltrating immune cells play a key role against cancer. However, malignant cells are
able to evade the immune response and establish a very complex balance in which different …

Nano-enabled pancreas cancer immunotherapy using immunogenic cell death and reversing immunosuppression

J Lu, X Liu, YP Liao, F Salazar, B Sun, W Jiang… - Nature …, 2017 - nature.com
While chemotherapy delivery by nanocarriers has modestly improved the survival prospects
of pancreatic ductal adenocarcinoma (PDAC), additional engagement of the immune …

Shortwave-infrared-light-emitting probes for the in vivo tracking of cancer vaccines and the elicited immune responses

F Ren, F Wang, A Baghdasaryan, Y Li, H Liu… - Nature biomedical …, 2024 - nature.com
Tracking and imaging immune cells in vivo non-invasively would offer insights into the
immune responses induced by vaccination. Here we report a cancer vaccine consisting of …

Cellular senescence in cancer: from mechanisms to detection

HL Ou, R Hoffmann, C González‐López… - Molecular …, 2021 - Wiley Online Library
Senescence refers to a cellular state featuring a stable cell‐cycle arrest triggered in
response to stress. This response also involves other distinct morphological and intracellular …

An effective immuno-PET imaging method to monitor CD8-dependent responses to immunotherapy

R Tavaré, H Escuin-Ordinas, S Mok, MN McCracken… - Cancer research, 2016 - AACR
The rapidly advancing field of cancer immunotherapy is currently limited by the scarcity of
noninvasive and quantitative technologies capable of monitoring the presence and …

Activatable Sonoafterglow Nanoprobes for T‐Cell Imaging

C Xu, S He, X Wei, J Huang, M Xu, K Pu - Advanced Materials, 2023 - Wiley Online Library
Real‐time imaging of immune systems benefits early diagnosis of disease and precision
immunotherapy; however, most existing imaging probes either have “always‐on” signals …

PET/MR imaging of inflammation in atherosclerosis

ML Senders, C Calcagno, A Tawakol… - Nature Biomedical …, 2023 - nature.com
Myocardial infarction, stroke, mental disorders, neurodegenerative processes, autoimmune
diseases, cancer and the human immunodeficiency virus impact the haematopoietic system …

Current Perspectives on 89Zr-PET Imaging

JK Yoon, BN Park, EK Ryu, YS An, SJ Lee - International Journal of …, 2020 - mdpi.com
89Zr is an emerging radionuclide that plays an essential role in immuno-positron emission
tomography (PET) imaging. The long half-life of 89Zr (t1/2= 3.3 days) is favorable for …