Obsessive-compulsive disorder is a severe and disabling psychiatric disorder that presents
several challenges for neuroscience. Recent advances in its genetic and developmental …

Self-grooming is a complex innate behaviour with an evolutionarily conserved sequencing
pattern and is one of the most frequently performed behavioural activities in rodents. In this …

Serotonin reuptake inhibitor (SRI) medications are well established as first-line
pharmacotherapeutic treatment for Obsessive-Compulsive Disorder (OCD). However …

Striatal dopamine (DA) is thought to code for learned associations between cues and
reinforcers and to mediate approach behavior toward a reward. Less is known about the …

Compulsive behaviors are driven by repetitive urges and typically involve the experience of
limited voluntary control over these urges, a diminished ability to delay or inhibit these …

Compulsions are repetitive, stereotyped thoughts and behaviors designed to reduce harm.
Growing evidence suggests that the neurocognitive mechanisms mediating behavioral …

Autism spectrum disorder (ASD) is comprised of several conditions characterized by
alterations in social interaction, communication, and repetitive behaviors. Genetic and …

Background and Aims Recent studies have challenged the anxiety-avoidance model of
obsessive–compulsive disorder (OCD), linking OCD to impulsivity, risky-decision-making …

Gilles de la Tourette syndrome (TS) is characterized by tics, which are transiently worsened
by stress, acute administration of dopaminergic drugs, and by subtle deficits in motor …

Tourette syndrome (TS) is thought to involve dopaminergic disturbances, but the nature of
those disturbances remains controversial. Existing hypotheses suggest that TS involves 1) …