Mechanisms of lipid droplet accumulation in steatotic liver diseases

JL Dempsey, GN Ioannou… - Seminars in Liver Disease, 2023 - thieme-connect.com
The steatotic diseases of metabolic dysfunction-associated steatotic liver disease (MASLD),
alcohol-associated liver disease (ALD), and chronic hepatitis C (HCV) account for the …

[PDF][PDF] 脂肪酸代谢在结直肠癌肿瘤微环境中的研究进展

张筱, 袁正, 林光武 - 肿瘤影像学, 2022 - zhongliuyingxiangxue.com
近几年来, 结直肠癌在中国的发病率呈逐年升高的趋势, 发病人群也趋于年轻化,
并且它被认为是一种肥胖相关癌症. 这是由于现代研究证明脂肪组织不仅仅是多余热量的储存库 …

Transcriptional regulation of Dyskerin via canonical WNT signaling modulates sphingolipid biosynthesis and drives colorectal cancer

S Nigam, UK Khan, A Praveen, A Shendre… - bioRxiv, 2023 - biorxiv.org
Targeting EGFR has been effective in RAS/RAF wild-type colorectal cancer (CRC) patients.
However, residual tumor relapses, necessitating the importance of biomarker-guided novel …

Canonical WNT signaling-driven DKC1 dysregulates sphingolipid biosynthesis and drives colorectal cancer.

B Ateeq, S Nigam, U Khan, A Praveen, A Shendre… - 2023 - researchsquare.com
Aberrant activation of canonical WNT signaling has been implicated in colorectal cancer
(CRC) progression. However, the complexity associated with WNT pathway poses …