A physiological level of oxygen/nitrogen free radicals and non-radical reactive species
(collectively known as ROS/RNS) is termed oxidative eustress or “good stress” and is …

It has long been recognized that an increase of reactive oxygen species (ROS) can modify
the cell‐signaling proteins and have functional consequences, which successively mediate …

Ca2+ plays a crucial role in connecting membrane excitability with contraction in
myocardium. The hallmark features of heart failure are mechanical dysfunction and …

Mitochondrial alterations are critically involved in increased vulnerability to disease during
aging. We investigated the contribution of mitochondria–sarcoplasmic reticulum (SR) …

Photobiomodulation (PBM) is the use of low irradiance light of specific wavelengths to
generate physiological changes and therapeutic effects. However, there are few studies on …

Spatio-temporal dynamics of intracellular calcium,[Ca2+] i, regulate the contractile function
of cardiac muscle cells. Measuring [Ca2+] i flux is central to the study of mechanisms that …

Recent electron microscopy data have revealed that cardiac mitochondria are not arranged
in crystalline columns but are organised with several mitochondria aggregated into columns …

Mitochondrial disease resulting in reduced bioenergetic output can be due to mutations in
either nuclear DNA–encoded or mitochondrial DNA–encoded gene products. We …

Experimental characterization of two cardiac mitochondrial subpopulations, namely,
subsarcolemmal mitochondria (SSM) and interfibrillar mitochondria (IFM), has been …

In cardiac cells, calcium is the mediator of excitation-contraction coupling. Dysfunctions in
calcium handling have been identified as the origin of some cardiac arrhythmias. In the …