Acute kidney injury in patients with cancer

MH Rosner, MA Perazella - New England Journal of Medicine, 2017 - Mass Medical Soc
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Trends in prevalence of chronic kidney disease in the United States

D Murphy, CE McCulloch, F Lin, T Banerjee… - Annals of internal …, 2016 - acpjournals.org
Background: Trends in the prevalence of chronic kidney disease (CKD) are important for
health care policy and planning. Objective: To update trends in CKD prevalence. Design …

Myeloma light chain cast nephropathy, a review

IJ Sathick, ME Drosou, N Leung - Journal of Nephrology, 2019 - Springer
Multiple Myeloma is a plasma cell proliferative disorder that commonly involves the kidney.
Renal impairment is a serious complication during the course of the disease that is …

Acute kidney injury in patients receiving systemic treatment for cancer: a population-based cohort study

A Kitchlu, E McArthur, E Amir, CM Booth… - JNCI: Journal of the …, 2019 - academic.oup.com
Background Patients undergoing treatment for cancer are at increased risk of acute kidney
injury (AKI). There are few data on AKI incidence and risk factors in the current era of cancer …

Immunoglobulin light chains generate proinflammatory and profibrotic kidney injury

WZ Ying, X Li, S Rangarajan, W Feng… - The Journal of …, 2019 - Am Soc Clin Investig
Because of the less-than-robust response to therapy and impact on choice of optimal
chemotherapy and prognosis, chronic kidney disease has drawn attention in the treatment of …

Paraprotein–related kidney disease: evaluation and treatment of myeloma cast nephropathy

KW Finkel, EP Cohen, A Shirali… - Clinical Journal of the …, 2016 - journals.lww.com
Nearly 50% of patients with multiple myeloma develop renal disease, most commonly from
AKI caused by cast nephropathy. Development of AKI is associated with poor 1-year survival …

[HTML][HTML] The proximal tubule toxicity of immunoglobulin light chains

C Sirac, V Batuman, PW Sanders - Kidney international reports, 2021 - Elsevier
Plasma and B cells dyscrasias that overproduce monoclonal immunoglobulin free light
chains (FLC) affect the kidney frequently in various ways. The hematologic dyscrasia …

[HTML][HTML] Kidney transplant outcomes of patients with multiple myeloma

C Heybeli, AJ Bentall, MP Alexander, H Amer… - Kidney International …, 2022 - Elsevier
Introduction Data on kidney transplantation (KTx) outcomes of patients with multiple
myeloma (MM) are very limited. Methods We investigated the outcomes of patients with MM …

Light chains removal by extracorporeal techniques in acute kidney injury due to multiple myeloma: a position statement of the Onconephrology Work Group of the …

P Fabbrini, K Finkel, M Gallieni, G Capasso… - Journal of …, 2016 - Springer
Acute kidney injury (AKI) is a frequent complication of multiple myeloma and is associated
with increased short-term mortality. Additionally, even a single episode of AKI can eventually …

[HTML][HTML] Intratubular amyloid in light chain cast nephropathy is a risk factor for systemic light chain amyloidosis

JB Gibier, V Gnemmi, F Glowacki, EM Boyle, B Lopez… - Modern Pathology, 2018 - Elsevier
Light chain cast nephropathy is the most common form of kidney disease in patients with
multiple myeloma. Light chain casts may occasionally show amyloid staining properties, that …