Host and bacterial factors linking periodontitis and rheumatoid arthritis

A Krutyhołowa, K Strzelec, A Dziedzic… - Frontiers in …, 2022 - frontiersin.org
Observations from numerous clinical, epidemiological and serological studies link
periodontitis with severity and progression of rheumatoid arthritis. The strong association is …

Virulence factors of the oral spirochete Treponema denticola

SG Dashper, CA Seers, KH Tan… - Journal of dental …, 2011 - journals.sagepub.com
There is compelling evidence that treponemes are involved in the etiology of several chronic
diseases, including chronic periodontitis as well as other forms of periodontal disease …

Activation of antibacterial autophagy by NADPH oxidases

J Huang, V Canadien, GY Lam… - Proceedings of the …, 2009 - National Acad Sciences
Autophagy plays an important role in immunity to microbial pathogens. The autophagy
system can target bacteria in phagosomes, promoting phagosome maturation and …

Human neutrophils and oral microbiota: a constant tug‐of‐war between a harmonious and a discordant coexistence

SM Uriarte, JS Edmisson… - Immunological …, 2016 - Wiley Online Library
Neutrophils are a major component of the innate host response, and the outcome of the
interaction between the oral microbiota and neutrophils is a key determinant of oral health …

Interactions between neutrophils and periodontal pathogens in late-onset periodontitis

Q Jiang, Y Zhao, Y Shui, X Zhou, L Cheng… - Frontiers in cellular …, 2021 - frontiersin.org
Late-onset periodontitis is associated with a series of inflammatory reactions induced by
periodontal pathogens, such as Porphyromonas gingivalis, a keystone pathogen involved in …

Virulence factors of Treponema denticola.

K Ishihara - Periodontology 2000, 2010 - search.ebscohost.com
The article focuses on the virulence factors of Treponema denticola including major outer
sheath protein (Msp) and dentilisin which were analyzed using molecular genetic …

[HTML][HTML] Complementary Tolls in the periodontium: how periodontal bacteria modify complement and Toll-like receptor responses to prevail in the host

JL Krauss, J Potempa, JD Lambris… - Periodontology …, 2010 - ncbi.nlm.nih.gov
The complement and the Toll-like receptors are rapidly activatable systems which, in
concert, provide first-line innate defense against infection and act as mediators between the …

[HTML][HTML] New insights into the emerging role of oral spirochaetes in periodontal disease

MB Visser, RP Ellen - Clinical Microbiology and Infection, 2011 - Elsevier
Spirochaetes are prominent in the polymicrobial infections that cause periodontal diseases.
Periodontitis is a chronic inflammatory condition of the periodontium, characterized by …

Aquaporin 9 phosphorylation mediates membrane localization and neutrophil polarization

T Karlsson, M Glogauer, RP Ellen… - Journal of leukocyte …, 2011 - academic.oup.com
Neutrophils are of prime importance in the host innate defense against invading
microorganisms by using two primary mechanisms—locomotion toward and phagocytosis of …

Periodontal Pathogens' strategies disarm neutrophils to promote dysregulated inflammation

I Miralda, SM Uriarte - Molecular oral microbiology, 2021 - Wiley Online Library
Periodontitis is an irreversible, chronic inflammatory disease where inflammophilic
pathogenic microbial communities accumulate in the gingival crevice. Neutrophils are a …