Obesity and diabetes now considered global epidemics. The prevalence rates of diabetes
are increasing in parallel with the rates of obesity and the strong connection between these …

Phosphoinositides (PIs) make up only a small fraction of cellular phospholipids, yet they
control almost all aspects of a cell's life and death. These lipids gained tremendous research …

Starting out as a model for developmental biology, during the last decade, zebrafish have
also gained the attention of the immunologists and oncologists. Due to its small size, high …

Dysregulation of the inflammatory response in humans can lead to various inflammatory
diseases, like asthma and rheumatoid arthritis. The innate branch of the immune system …

The zebrafish research community is celebrating! The zebrafish genome has recently been
sequenced, the Zebrafish Mutation Project (launched by the Wellcome Trust Sanger …

Non-alcoholic fatty liver disease encompasses a spectrum of liver diseases, including
simple steatosis, steatohepatitis, liver fibrosis and cirrhosis and hepatocellular carcinoma …

Mitochondrial dynamics regulated by mitochondrial fusion and fission maintain
mitochondrial functions, whose alterations underline various human diseases. Here, we …

Polyphosphoinositides are lipid signaling molecules generated from phosphatidylinositol
(PtdIns) with critical roles in vesicular trafficking and signaling. It is poorly understood where …

The zebrafish has emerged as a powerful vertebrate model for studying liver‐associated
disorders. Liver damage is a crucial problem in the process of drug development and …

In this study, for the first time, changes in expressions of proteins and profiles of metabolites
in liver of the small, freshwater fish Danio rerio (zebrafish) were investigated after long-term …