This guideline presents recommendations for the management of patients with hereditary
gastrointestinal cancer syndromes. The initial assessment is the collection of a family history …

Melanoma is the most deadly of the common skin cancers and its incidence is rapidly
increasing. Approximately 10% of cases occur in a familial context. To date, cyclin …

The incidence of primary cutaneous melanoma continues to increase each year. Melanoma
accounts for the majority of skin cancer–related deaths, but treatment is usually curative …

Skin cancer affects the lives of millions of people every year, as it is considered the most
popular form of cancer. In the USA alone, approximately three and a half million people are …

Malignant melanoma is considered the most lethal skin cancer if it is not detected and
treated during its early stages. About 10% of melanoma patients report a family history of …

These guidelines reflect the best published data available at the time the report was
prepared. Caution should be exercised in interpreting the data; the results of future studies …

The incidence of primary cutaneous melanoma has been increasing dramatically for several
decades. Melanoma accounts for the majority of skin cancer–related deaths, but treatment is …

Although CDKN2A is well-known as a susceptibility gene for melanoma and pancreatic
cancer, germline variants have also been anecdotally associated with a broader range of …

Cutaneous melanoma is responsible for the vast majority of skin cancer-related deaths in
the United States. Known risk factors include genetic defects, environmental exposures, and …

Several distinct melanoma syndromes have been defined, and genetic tests are available
for the associated causative genes. Guidelines for melanoma genetic testing have been …