Comprehensive computational studies of naturally occurring kuguacins as antidiabetic agents by targeting visfatin
Diabetes mellitus continues to be a major health concern for the global population.
Targeting visfatin has been identified as a possible channel to manage the disease …
Targeting visfatin has been identified as a possible channel to manage the disease …
Optimization of microwave-assisted extraction (MAE) of key phenolic compounds from pigeon pea (Cajanus cajan L.), their characterization, and measurement of …
The current work aims to optimize and develop a scale-up process design for higher yields
of phenolic compounds, as well as propose and validate their antidiabetic and cytotoxic …
of phenolic compounds, as well as propose and validate their antidiabetic and cytotoxic …
[HTML][HTML] Elucidating the glucokinase activating potentials of naturally occurring prenylated flavonoids: an explicit computational approach
KO Faloye, BD Bekono, EG Fakola, MD Ayoola… - Molecules, 2021 - mdpi.com
Glucokinase activators are considered as new therapeutic arsenals that bind to the allosteric
activator sites of glucokinase enzymes, thereby maximizing its catalytic rate and increasing …
activator sites of glucokinase enzymes, thereby maximizing its catalytic rate and increasing …
Evaluation of the Antidiabetic Activities of the Fruit of Parquetina nigrescens (Afzel.) Bullock and In Silico Identification of Its Antidiabetic Agent
MD Ayoola, YB Ogundeko… - … and Biology Insights, 2024 - journals.sagepub.com
The study investigated the antidiabetic potentials of the fruit extract of Parquetina nigrescens
with the aim of justifying its folkloric antidiabetic usage in some part of Nigeria. Acute toxicity …
with the aim of justifying its folkloric antidiabetic usage in some part of Nigeria. Acute toxicity …
Investigating the multitargeted anti-diabetic potential of cucurbitane-type triterpenoid from Momordica charantia: an LC-MS, docking-based MM\GBSA and MD …
Type 2 diabetes accounts for the largest percentage of all diabetic cases worldwide.
Cucurbitane-type triterpenes are mainly found in Momordica charantia and possess …
Cucurbitane-type triterpenes are mainly found in Momordica charantia and possess …
[HTML][HTML] The antihyperglycemic potential of pyrazolobenzothiazine 1, 1-dioxide novel derivative in mice using integrated molecular pharmacological approach
Diabetes Mellitus is a metabolic disease characterized by elevated blood sugar levels
caused by inadequate insulin production, which subsequently leads to hyperglycemia. This …
caused by inadequate insulin production, which subsequently leads to hyperglycemia. This …
Exploring the protein tyrosine phosphatase 1B inhibitory potentials of naturally occurring Brazilin-type homoisoflavonoids: a computational approach
IO Awotuya, EG Fakola, AJ Olusola, EA Olanudun… - Chemistry Africa, 2022 - Springer
Diabetes mellitus is a disease that continues to pose serious health challenges to the
world's population. Protein tyrosine phosphatase 1B (PTP1B) is an enzyme that plays …
world's population. Protein tyrosine phosphatase 1B (PTP1B) is an enzyme that plays …
Antimalarial potential, LC–MS secondary metabolite profiling and computational studies of Zingiber officinale
KO Faloye, MK Tripathi, SA Adesida… - Journal of …, 2024 - Taylor & Francis
Malaria is among the top-ranked parasitic diseases that pose a threat to the existence of the
human race. This study evaluated the antimalarial effect of the rhizome of Zingiber officinale …
human race. This study evaluated the antimalarial effect of the rhizome of Zingiber officinale …
Synthesis, α-Glucosidase, α-Amylase, and Aldol Reductase Inhibitory Activity with Molecular Docking Study of Novel Imidazo[1,2-a]pyridine Derivatives
Inhibition ofaldose reductase (AR), α-glycosidase (α-GLY), and α-amylase (α-AMY) are
some of the essential targets in diabetes mellitus (DM). Here, a series of imidazo [1, 2-a] …
some of the essential targets in diabetes mellitus (DM). Here, a series of imidazo [1, 2-a] …
In Silico Exploration of Isoxazole Derivatives of Usnic Acid: Novel Therapeutic Prospects Against α-Amylase for Diabetes Treatment
Diabetes mellitus (DM) a metabolic disorder characterized by high blood sugar levels
causing damage to various organs over time. Current anti-diabetic drugs have limitations …
causing damage to various organs over time. Current anti-diabetic drugs have limitations …