[HTML][HTML] Gut microbiome and health: mechanistic insights
The gut microbiota is now considered as one of the key elements contributing to the
regulation of host health. Virtually all our body sites are colonised by microbes suggesting …
regulation of host health. Virtually all our body sites are colonised by microbes suggesting …
Gut microbiota in human metabolic health and disease
Y Fan, O Pedersen - Nature Reviews Microbiology, 2021 - nature.com
Observational findings achieved during the past two decades suggest that the intestinal
microbiota may contribute to the metabolic health of the human host and, when aberrant, to …
microbiota may contribute to the metabolic health of the human host and, when aberrant, to …
[HTML][HTML] Rethinking healthy eating in light of the gut microbiome
Given the worldwide epidemic of diet-related chronic diseases, evidence-based dietary
recommendations are fundamentally important for health promotion. Despite the importance …
recommendations are fundamentally important for health promotion. Despite the importance …
Non-alcoholic fatty liver disease: pathophysiological concepts and treatment options
C Grander, F Grabherr, H Tilg - Cardiovascular Research, 2023 - academic.oup.com
The prevalence of non-alcoholic fatty liver disease (NAFLD) is continually increasing due to
the global obesity epidemic. NAFLD comprises a systemic metabolic disease accompanied …
the global obesity epidemic. NAFLD comprises a systemic metabolic disease accompanied …
Interplay between diet, the gut microbiome, and atherosclerosis: Role of dysbiosis and microbial metabolites on inflammation and disordered lipid metabolism
L Anto, CN Blesso - The Journal of Nutritional Biochemistry, 2022 - Elsevier
Atherosclerosis remains the leading cause of death worldwide. Lifestyle modification,
including diet and exercise, is recommended to be the primary prevention strategy for …
including diet and exercise, is recommended to be the primary prevention strategy for …
Vascular endothelial tissue factor contributes to trimethylamine N-oxide-enhanced arterial thrombosis
M Witkowski, M Witkowski, J Friebel… - Cardiovascular …, 2022 - academic.oup.com
Aims Gut microbiota and their generated metabolites impact the host vascular phenotype.
The metaorganismal metabolite trimethylamine N-oxide (TMAO) is both associated with …
The metaorganismal metabolite trimethylamine N-oxide (TMAO) is both associated with …
[HTML][HTML] Propionate alleviates myocardial ischemia-reperfusion injury aggravated by angiotensin II dependent on caveolin-1/ACE2 axis through GPR41
F Deng, LQ Zhang, H Wu, Y Chen, WQ Yu… - … journal of biological …, 2022 - ncbi.nlm.nih.gov
Myocardial ischemia/reperfusion (I/R) injury is still a lack of effective therapeutic drugs, and
its molecular mechanism is urgently needed. Studies have shown that the intestinal flora …
its molecular mechanism is urgently needed. Studies have shown that the intestinal flora …
Contribution of the microbiome for better phenotyping of people living with obesity
Obesity has reached epidemic proportion worldwide and in all ages. Available evidence
points to a multifactorial pathogenesis involving gene predisposition and environmental …
points to a multifactorial pathogenesis involving gene predisposition and environmental …
Lycium barbarum polysaccharide attenuates myocardial injury in high-fat diet-fed mice through manipulating the gut microbiome and fecal metabolome
Z Zhang, H Liu, B Yu, H Tao, J Li, Z Wu, G Liu… - Food Research …, 2020 - Elsevier
High-fat diets (HFDs) can induce health problems including gut microbiota dysbiosis and
cardiac dysfunction. In this study, we modulated the gut microbiota in mice to investigate …
cardiac dysfunction. In this study, we modulated the gut microbiota in mice to investigate …
Gut metabolite trimethylamine-N-oxide in atherosclerosis: from mechanism to therapy
BY Wang, J Qiu, JF Lian, X Yang… - Frontiers in cardiovascular …, 2021 - frontiersin.org
Atherosclerosis is associated with various pathological manifestations, such as ischemic
heart disease, ischemic stroke, and peripheral arterial disease, and remains a leading …
heart disease, ischemic stroke, and peripheral arterial disease, and remains a leading …