Antimicrobial peptides (AMPs) are short, mainly positively charged, amphipathic molecules.
AMPs are important effectors of the immune response in insects with a broad spectrum of …

The microbiome includes both 'mutualist'and 'pathogen'microbes, regulated by the same
innate immune architecture. A major question has therefore been: how do hosts prevent …

Highlights•Cold-induced immune activation in insects remains poorly understood.•Oxidative
stress and damage-associated intracellular molecules may signal immunity.•Antimicrobial …

Host age variation is a striking source of heterogeneity that can shape the evolution and
transmission dynamic of pathogens. Compared with vertebrate systems, our understanding …

Both constitutive and inducible immune mechanisms are employed by hosts for defense
against infection. Constitutive immunity allows for a faster response, but it comes with an …

Invertebrates lack the immune machinery underlying vertebrate-like acquired immunity.
However, in many insects past infection by the same pathogen can 'prime'the immune …

The global demographic is shifting towards an aged population (United Nations, 2019). Yet,
it is our oldest members of society that are the most vulnerable to infectious disease …

Several mutations in the SOD1 gene encoding for the antioxidant enzyme Superoxide
Dismutase 1, are associated with amyotrophic lateral sclerosis, a rare and devastating …

Antimicrobial peptide (AMP) is an important component of crustaceans' innate immune
system. In this study, a short neuropeptide F (sNPF) gene (Pc-sNPF) and a Forkhead box O …

Invertebrates lack the specialized immune-memory cells responsible for vertebrate-like
acquired immunity. However, there is increasing evidence that past infection by the same …