Prevalence, risk factors, and clinical implications of preserved ratio impaired spirometry: a UK Biobank cohort analysis

DH Higbee, R Granell, GD Smith… - The Lancet Respiratory …, 2022 - thelancet.com
Background Preserved ratio impaired spirometry (PRISm) is defined as a FEV 1 of less than
80% predicted and a FEV 1/forced vital capacity (FVC) ratio of 0· 70 or higher. Previous …

Longitudinal phenotypes and mortality in preserved ratio impaired spirometry in the COPDGene study

ES Wan, S Fortis, EA Regan, J Hokanson… - American journal of …, 2018 - atsjournals.org
Rationale: Increasing awareness of the prevalence and significance of Preserved Ratio
Impaired Spirometry (PRISm), alternatively known as restrictive or Global Initiative for …

Lung dysfunction and mortality in patients with chronic kidney disease

H Mukai, P Ming, B Lindholm, O Heimbürger… - Kidney and Blood …, 2018 - karger.com
Abstract Background/Aims: Lung dysfunction associates with increased mortality but the
impact of chronic kidney disease (CKD) is less clear. We evaluated lung function and its …

Trajectory of preserved ratio impaired spirometry: natural history and long-term prognosis

JL Marott, TS Ingebrigtsen, Y Çolak… - American Journal of …, 2021 - atsjournals.org
Rationale: Natural history of preserved ratio impaired spirometry (PRISm), often defined as
FEV1/FVC⩾ lower limit of normal and FEV1< 80% of predicted value, is not well described …

Significant spirometric transitions and preserved ratio impaired spirometry among ever smokers

ES Wan, JE Hokanson, EA Regan, KA Young, BJ Make… - Chest, 2022 - Elsevier
Background Emerging data from longitudinal studies suggest that preserved ratio impaired
spirometry (PRISm), defined by proportionate reductions in FEV 1 and FVC, is a …

Preserved ratio impaired spirometry is associated with small airway dysfunction and reduced total lung capacity

N Zhao, F Wu, J Peng, Y Zheng, H Tian, H Yang… - Respiratory …, 2022 - Springer
Background: Preserved ratio impaired spirometry (PRISm) refers to decreased forced
expiratory volume in 1 s (FEV1) in the setting of preserved ratio. Little is known about the …

Preserved ratio impaired spirometry in relationship to cardiovascular outcomes: a large prospective cohort study

J Zheng, R Zhou, Y Zhang, K Su, H Chen, F Li… - Chest, 2023 - Elsevier
Background Preserved ratio impaired spirometry (PRISm) findings are a heterogeneous
condition characterized by a normal FEV 1 to FVC ratio with underlying impairment of …

Understanding COPD Etiology, Pathophysiology, and Definition

JL Curtis - Respiratory Care, 2023 - rc.rcjournal.com
COPD, one of the leading worldwide health problems, currently lacks truly disease-
modifying medical therapies applicable to most patients. Developing such novel therapies …

Environmental-level exposure to metals and metal-mixtures associated with spirometry-defined lung disease in American Indian adults: Evidence from the Strong …

M Sobel, A Navas-Acien, M Powers, M Grau-Perez… - Environmental …, 2022 - Elsevier
Abstract Background American Indians have a higher burden of chronic lung disease
compared to the US average. Several metals are known to induce chronic lung disease at …

Restricted spirometry and cardiometabolic comorbidities: results from the international population based BOLD study

K Kulbacka-Ortiz, FJJ Triest, FME Franssen… - Respiratory …, 2022 - Springer
Background Whether restricted spirometry, ie low Forced Vital Capacity (FVC), predicts
chronic cardiometabolic disease is not definitely known. In this international population …