Spectral imaging is a technology that integrates conventional imaging and spectroscopy to
get both spatial and spectral information from an object. Although this technology was …

Spatial frequency domain imaging (SFDI) has witnessed very rapid growth over the last
decade, owing to its unique capabilities for imaging optical properties and chromophores …

Background Veliparib is a potent small molecule inhibitor of PARP-1/2, which is cytotoxic in
tumor cells with deficiencies in BRCA1 or BRCA2. We studied the clinical activity and toxicity …

The authors describe the development of diffuse optical imaging (DOI) technologies,
specifically the use of spatial and temporal modulation to control near infrared light …

Breast conserving surgery (BCS) is an effective treatment for early-stage cancers as long as
the margins of the resected tissue are free of disease according to consensus guidelines for …

Rather than simply acting as a photographic camera capturing two‐dimensional (x, y)
intensity images or a spectrometer acquiring spectra (λ), a hyperspectral imager measures …

Diffuse optical imaging probes deep living tissue enabling structural, functional, metabolic,
and molecular imaging. Recently, due to the availability of spatial light modulators, wide …

Oxygenation measurements are widely used in patient care. However, most clinically
available instruments currently consist of contact probes that only provide global monitoring …

Water and lipids are key participants in many biological processes, but there are few non-
invasive methods that provide quantification of these components in vivo, and none that can …

We employ a clinical multiphoton microscope to monitor in vivo and noninvasively the
changes in reduced nicotinamide adenine dinucleotide (NADH) fluorescence of human …