In Vitro Cell Death Mechanisms Induced by Dicoma anomala Root Extract in Combination with ZnPcS4 Mediated-Photodynamic Therapy in A549 Lung Cancer Cells

A Chota, BP George, H Abrahamse - Cells, 2022 - mdpi.com
Globally, lung cancer has remained the leading cause of morbidity and mortality in men and
women. To enhance photodynamic therapeutic effects in vitro, the present study was …

The impact of general anesthesia on redox stability and epigenetic inflammation pathways: crosstalk on perioperative antioxidant therapy

SA Ritiu, AF Rogobete, D Sandesc, OH Bedreag… - Cells, 2022 - mdpi.com
Worldwide, the prevalence of surgery under general anesthesia has significantly increased,
both because of modern anesthetic and pain-control techniques and because of better …

Pitfalls of Mitochondrial Redox Signaling Research

P Ježek - Antioxidants, 2023 - mdpi.com
Redox signaling from mitochondria (mt) to the cytosol and plasma membrane (PM) has been
scarcely reported, such as in the case of hypoxic cell adaptation or (2-oxo-) 2-keto …

[HTML][HTML] Mitochondrial dysfunction following repeated administration of alprazolam causes attenuation of hippocampus-dependent memory consolidation in mice

S Zhu, J Shi, Q Jin, Y Zhang, R Zhang, X Chen… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
The frequently repeated administration of alprazolam (Alp), a highly effective
benzodiazepine sedative-hypnotic agent, in anxiety, insomnia, and other diseases is closely …

o8G Site-Specifically Modified tRF-1-AspGTC: A Novel Therapeutic Target and Biomarker for Pulmonary Hypertension

J Zhang, Y Li, Y Chen, J Zhang, Z Jia, M He… - Circulation …, 2024 - Am Heart Assoc
RATIONALE: Hypoxia and oxidative stress contribute to the development of pulmonary
hypertension (PH). tRNA-derived fragments play important roles in RNA interference and …

[HTML][HTML] Biomimetic Integrated Nanozyme for Flare and Recurrence of Gouty Arthritis

R Wang, T Liu, X Li, E Lu, Y Chen, K Luo… - Asian Journal of …, 2024 - Elsevier
Flare and multiple recurrences pose significant challenges in gouty arthritis. Traditional
treatments provide temporary relief from inflammation but fail to promptly alleviate patient …

[HTML][HTML] Hypoxia-Induced Mitochondrial ROS and Function in Pulmonary Arterial Endothelial Cells

H Wang, TY Song, J Reyes-García, YX Wang - Cells, 2024 - mdpi.com
Pulmonary artery endothelial cells (PAECs) are a major contributor to hypoxic pulmonary
hypertension (PH) due to the possible roles of reactive oxygen species (ROS). However, the …

Pulmonary Hypertension Secondary to Myxomatous Mitral Valve Disease in Dogs: Current Insights into the Histological Manifestation and Its Determining Factors

A Grzeczka, U Pasławska, S Graczyk, P Antosik… - Applied Sciences, 2024 - mdpi.com
Pulmonary venous hypertension (PVH) is caused by deteriorating left ventricular function.
The most common cause of PVH in dogs is myxomatous mitral valve degeneration (MMVD) …

Salidroside enhances NO bioavailability and modulates arginine metabolism to alleviate pulmonary arterial hypertension

J Li, Z Zhang, C Zhu, X Zheng, C Wang, J Jiang… - European Journal of …, 2024 - Springer
Background Salidroside (SAL), derived from Rhodiola, shows protective effects in
pulmonary arterial hypertension (PAH) models, but its mechanisms are not fully elucidated …

The Potential Important Role of Mitochondrial Rieske Iron–Sulfur Protein as a Novel Therapeutic Target for Pulmonary Hypertension in Chronic Obstructive Pulmonary …

L Truong, YM Zheng, YX Wang - Biomedicines, 2022 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death
worldwide, which is often due to pulmonary hypertension (PH). The underlying molecular …