No other tissue in the body depends more on the composition and organization of the
extracellular matrix (ECM) for normal structure and function than the corneal stroma. The …

Extracellular vesicles (EVs) are biological nanoparticles naturally secreted by cells, acting
as delivery vehicles for molecular messages. During the last decade, EVs have been …

Corneal stromal wound healing is a complex event that occurs to restore the transparency of
an injured cornea. It involves immediate apoptosis of keratocytes followed by their activation …

Exosomes are nanoscale monolayer membrane vesicles that are actively endogenously
secreted by mammalian cells. Currently, multifunctional exosomes with tumor-targeted …

Photoreceptor apoptosis is recognized as one key pathogenesis of retinal degeneration, the
counteraction of which represents a promising approach to safeguard visual function …

The corneal epithelium is continuously renewed by limbal stem/progenitor cells (LSCs), a
cell population harbored in a highly regulated niche located at the limbus. Dysfunction …

Aims The management of acute liver failure (ALF) is a major challenge worldwide. The
current study aimed to determine the therapeutic potential of TNF-α pretreatment of umbilical …

Aniridia, a rare congenital disease, is often characterized by a progressive, pronounced
limbal insufficiency and ocular surface pathology termed aniridia-associated keratopathy …

Background: Since the cornea is responsible for transmitting and focusing light into the eye,
injury or pathology affecting any layer of the cornea can cause a detrimental effect on visual …

Exosomes are natural extracellular vesicles with a diameter of 30–150 nm, which exist in
biological fluids and contain biomolecules related to the parent cell, such as proteins …