Is oxytocin “nature's medicine”?

CS Carter, WM Kenkel, EL MacLean, SR Wilson… - Pharmacological …, 2020 - ASPET
Oxytocin is a pleiotropic, peptide hormone with broad implications for general health,
adaptation, development, reproduction, and social behavior. Endogenous oxytocin and …

The oxytocin receptor: from intracellular signaling to behavior

B Jurek, ID Neumann - Physiological reviews, 2018 - journals.physiology.org
The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …

Glucose metabolism links astroglial mitochondria to cannabinoid effects

D Jimenez-Blasco, A Busquets-Garcia… - Nature, 2020 - nature.com
Astrocytes take up glucose from the bloodstream to provide energy to the brain, thereby
allowing neuronal activity and behavioural responses,,,–. By contrast, astrocytes are under …

[HTML][HTML] Brain oxytocin: how puzzle stones from animal studies translate into psychiatry

V Grinevich, ID Neumann - Molecular psychiatry, 2021 - nature.com
The neuropeptide oxytocin has attracted great attention of the general public, basic
neuroscience researchers, psychologists, and psychiatrists due to its profound pro-social …

[HTML][HTML] Oxytocin in general anxiety and social fear: a translational approach

ID Neumann, DA Slattery - Biological psychiatry, 2016 - Elsevier
The neuropeptide oxytocin (OXT) has been revealed as a profound anxiolytic and antistress
factor of the brain, besides its many prosocial and reproductive effects. Therefore, there is …

[HTML][HTML] Self-soothing behaviors with particular reference to oxytocin release induced by non-noxious sensory stimulation

K Uvnäs-Moberg, L Handlin - Frontiers in psychology, 2015 - frontiersin.org
Oxytocin, a hypothalamic nonapeptide, is linked to increased levels of social interaction, well-
being and anti-stress effects. The effects of oxytocin that is released by sensory stimulation …

[HTML][HTML] Autism, oxytocin and interoception

E Quattrocki, K Friston - Neuroscience & Biobehavioral Reviews, 2014 - Elsevier
Autism is a pervasive developmental disorder characterized by profound social and verbal
communication deficits, stereotypical motor behaviors, restricted interests, and cognitive …

[HTML][HTML] Negative symptoms of schizophrenia: clinical characteristics, pathophysiological substrates, experimental models and prospects for improved treatment

MJ Millan, K Fone, T Steckler, WP Horan - European …, 2014 - Elsevier
Schizophrenia is a complex and multifactorial disorder generally diagnosed in young adults
at the time of the first psychotic episode of delusions and hallucinations. These positive …

[HTML][HTML] Oxytocin signaling in the central amygdala modulates emotion discrimination in mice

V Ferretti, F Maltese, G Contarini, M Nigro, A Bonavia… - Current Biology, 2019 - cell.com
Recognition of other's emotions influences the way social animals interact and adapt to the
environment. The neuropeptide oxytocin (OXT) has been implicated in different aspects of …

Somatostatin interneurons in the prefrontal cortex control affective state discrimination in mice

D Scheggia, F Managò, F Maltese, S Bruni… - Nature …, 2020 - nature.com
The prefrontal cortex (PFC) is implicated in processing of the affective state of others through
non-verbal communication. This social cognitive function is thought to rely on an intact …