Short-chain fatty acids, maternal microbiota and metabolism in pregnancy

M Ziętek, Z Celewicz, M Szczuko - Nutrients, 2021 - mdpi.com
Short-chain fatty acids (SCFAs), as products of intestinal bacterial metabolism, are
particularly relevant in the diagnosis of intestinal dysbiosis. The most common studies of …

Paternal preconception modifiable risk factors for adverse pregnancy and offspring outcomes: a review of contemporary evidence from observational studies

T Carter, D Schoenaker, J Adams, A Steel - BMC Public Health, 2023 - Springer
Background The preconception period represents transgenerational opportunities to
optimize modifiable risk factors associated with both short and long-term adverse health …

Gestational diabetes is uniquely associated with altered early seeding of the infant gut microbiota

TK Soderborg, CM Carpenter, RC Janssen… - Frontiers in …, 2020 - frontiersin.org
Gestational diabetes mellitus (GDM) is a worldwide public health problem affecting up to
27% of pregnancies with high predictive values for childhood obesity and inflammatory …

Influence of increased paternal BMI on pregnancy and child health outcomes independent of maternal effects: A systematic review and meta-analysis

JM Campbell, NO McPherson - Obesity research & clinical practice, 2019 - Elsevier
Objectives The influence of maternal body mass index (BMI) on pregnancy and child health
outcomes is well characterised, however less is known about paternal BMI. This systematic …

Type 2 diabetes in youth: the role of early life exposures

A Rughani, JE Friedman, JB Tryggestad - Current diabetes reports, 2020 - Springer
Abstract Purpose of Review This review examines the impact of early life exposures on
glucose metabolism in the offspring and explores potential metabolic mechanisms leading …

Developmental programming of peripheral diseases in offspring exposed to maternal obesity during pregnancy

N Shrestha, HC Ezechukwu… - American Journal of …, 2020 - journals.physiology.org
Obesity is an increasing global health epidemic that affects all ages, including women of
reproductive age. During pregnancy, maternal obesity is associated with adverse pregnancy …

Association of maternal prepregnancy weight and gestational weight gain with children's allergic diseases

Y Chen, J Zhu, J Lyu, Y Xia, Y Ying, Y Hu… - JAMA Network …, 2020 - jamanetwork.com
Importance Information on the association between maternal prepregnancy body weight,
gestational weight change, and childhood allergies is not consistent. Little is known on …

Diet-induced modification of the sperm epigenome programs metabolism and behavior

C Bodden, AJ Hannan, AC Reichelt - Trends in Endocrinology & …, 2020 - cell.com
Globally, obesity has reached epidemic proportions. The rapidly increasing numbers of
overweight people can be traced back to overconsumption of energy-dense, poor-quality …

Maternal effects in mammals: broadening our understanding of offspring programming

PD Edwards, SG Lavergne, LK McCaw… - Frontiers in …, 2021 - Elsevier
The perinatal period is a sensitive time in mammalian development that can have long-
lasting consequences on offspring phenotype via maternal effects. Maternal effects have …

Maternal obesity, gestational weight gain, and offspring asthma and atopy

KJ Polinski, GA Bell, MH Trinh, R Sundaram… - Annals of Allergy …, 2022 - Elsevier
Background Maternal obesity may affect offspring asthma and atopic disease risk by altering
fetal immune system development. However, few studies evaluate gestational weight gain …