Strategies for targeted drug delivery in treatment of colon cancer: current trends and future perspectives

A Banerjee, S Pathak, VD Subramanium… - Drug discovery today, 2017 - Elsevier
Highlights•Review summarizes the current status of colon cancer and its management
strategies.•Features nanoformulated targeted delivery of anticancer drugs for colon cancer …

Current-status and applications of polysaccharides in drug delivery systems

P Prasher, M Sharma, M Mehta, S Satija… - Colloid and Interface …, 2021 - Elsevier
The polysaccharide-based advanced drug delivery system owing to their biocompatibility,
ability to encapsulate the drug molecules in their interspaces, and ability to achieve a …

Targeted nanoparticles for colorectal cancer

BA Cisterna, N Kamaly, WI Choi, A Tavakkoli… - …, 2016 - Taylor & Francis
Colorectal cancer (CRC) is highly prevalent worldwide, and despite notable progress in
treatment still leads to significant morbidity and mortality. The use of nanoparticles as a drug …

Folate-conjugated nanovehicles: Strategies for cancer therapy

B Farran, RC Montenegro, P Kasa, E Pavitra… - Materials Science and …, 2020 - Elsevier
Cancer theranostics represents a strategy that aims at combining diagnosis with therapy
through the simultaneous imaging and targeted delivery of therapeutics to cancer cells …

[HTML][HTML] Insight to drug delivery aspects for colorectal cancer

A Gulbake, A Jain, A Jain, A Jain… - World journal of …, 2016 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the third most common cancer diagnosed worldwide in human
beings. Surgery, chemotherapy, radiotherapy and targeted therapies are the conventional …

Development and optimization of methotrexate-loaded lipid-polymer hybrid nanoparticles for controlled drug delivery applications

N Tahir, A Madni, V Balasubramanian… - International journal of …, 2017 - Elsevier
Lipid-polymer hybrid nanoparticles (LPHNPs) are emerging platforms for drug delivery
applications. In the present study, methotrexate loaded LPHNPs consisted of PLGA and …

Recent updates in the polysaccharides-based Nano-biocarriers for drugs delivery and its application in diseases treatment: A review

J Zhang, P Zhan, H Tian - International Journal of Biological …, 2021 - Elsevier
With people's increasing awareness of diseases treatment, the researchers began to focus
on drug delivery to the exact site of action at the optimal rate. Some researchers have …

Stimuli-responsive natural gums-based drug delivery systems for cancer treatment

K Soleimani, H Derakhshankhah, M Jaymand… - Carbohydrate …, 2021 - Elsevier
Chemotherapy as the main cancer treatment method has non-specific effects and various
side-effects. Accordingly, significant attempts have been conducted to enhance its efficacy …

Folic acid-chitosan functionalized polymeric nanocarriers to treat colon cancer

NA Bhaskaran, SR Jitta, L Kumar, P Sharma… - International Journal of …, 2023 - Elsevier
In the present study, polymeric nanoparticles loaded with IRI and quercetin, a p-gp inhibitor,
were developed to target folate receptors expressed by colon cancer cells for oral targeted …

Nanotechnology is an important strategy for combinational innovative chemo-immunotherapies against colorectal cancer

AI Matos, B Carreira, C Peres, LIF Moura… - Journal of Controlled …, 2019 - Elsevier
Colorectal cancer (CRC) is among the five most commonly diagnosed cancers worldwide,
constituting 6% of all cancers and the third leading cause of cancer death. CRC is the third …