[HTML][HTML] Designing spatial and temporal control of vaccine responses
Vaccines are the key technology to combat existing and emerging infectious diseases.
However, increasing the potency, quality and durability of the vaccine response remains a …
However, increasing the potency, quality and durability of the vaccine response remains a …
[HTML][HTML] Leukocyte trafficking to the lungs and beyond: lessons from influenza for COVID-19
R Alon, M Sportiello, S Kozlovski, A Kumar… - Nature Reviews …, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
coronavirus disease 2019 (COVID-19). Understanding of the fundamental processes …
coronavirus disease 2019 (COVID-19). Understanding of the fundamental processes …
[HTML][HTML] Clinical features predicting mortality risk in patients with viral pneumonia: the MuLBSTA score
L Guo, D Wei, X Zhang, Y Wu, Q Li, M Zhou… - Frontiers in …, 2019 - frontiersin.org
Objective The aim of this study was to further clarify clinical characteristics and predict
mortality risk among patients with viral pneumonia. Methods A total of 528 patients with viral …
mortality risk among patients with viral pneumonia. Methods A total of 528 patients with viral …
[HTML][HTML] Human CD8+ T cell cross-reactivity across influenza A, B and C viruses
Abstract Influenza A, B and C viruses (IAV, IBV and ICV, respectively) circulate globally and
infect humans, with IAV and IBV causing the most severe disease. CD8+ T cells confer cross …
infect humans, with IAV and IBV causing the most severe disease. CD8+ T cells confer cross …
[HTML][HTML] Advances in development and application of influenza vaccines
J Chen, J Wang, J Zhang, H Ly - Frontiers in immunology, 2021 - frontiersin.org
Influenza A virus is one of the most important zoonotic pathogens that can cause severe
symptoms and has the potential to cause high number of deaths and great economic loss …
symptoms and has the potential to cause high number of deaths and great economic loss …
Dynamic balance of pro‐and anti‐inflammatory signals controls disease and limits pathology
Immune responses to pathogens are complex and not well understood in many diseases,
and this is especially true for infections by persistent pathogens. One mechanism that allows …
and this is especially true for infections by persistent pathogens. One mechanism that allows …
Is a universal influenza virus vaccine possible?
R Nachbagauer, P Palese - Annual review of medicine, 2020 - annualreviews.org
Influenza viruses remain a severe burden to human health because of their contribution to
overall morbidity and mortality. Current seasonal influenza virus vaccines do not provide …
overall morbidity and mortality. Current seasonal influenza virus vaccines do not provide …
[HTML][HTML] Challenges at the Time of COVID-19: Opportunities and Innovations in Antivirals from Nature
As viral infections are an increasing threat to human societies, the need for new therapeutic
strategies is becoming even more obvious. As no vaccine is available for COVID-19, the …
strategies is becoming even more obvious. As no vaccine is available for COVID-19, the …
[HTML][HTML] Immune control of avian influenza virus infection and its vaccine development
P Dey, A Ahuja, J Panwar, P Choudhary, S Rani… - Vaccines, 2023 - mdpi.com
The avian influenza A virus (AIV) is naturally prevalent in aquatic birds, infecting different
avian species and transmitting from birds to humans. Both AIVs, the H5N1 and H7N9 …
avian species and transmitting from birds to humans. Both AIVs, the H5N1 and H7N9 …
[HTML][HTML] Downregulation of MHC class I expression by influenza A and B viruses
Manipulation of the MHC-I presentation pathway, and thus limiting MHC-I cell surface
expression, is used by many viruses to evade immune recognition. In particular …
expression, is used by many viruses to evade immune recognition. In particular …