Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that recently re-emerged in
many parts of the world causing large-scale outbreaks. CHIKV infection presents as a febrile …

Background The coronavirus disease 2019 (COVID-19) caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to plague the world. While …

Chikungunya virus (CHIKV) infection causes acute disease characterized by fever, rash and
arthralgia, which progresses to severe and chronic arthritis in up to 50% of patients …

Virus-like particle (VLP) is a self-assembled nanostructure incorporating key viral structural
proteins. VLP resembles molecular and morphological features of authentic viruses but is …

Vaccines are one of the most significant medical interventions in the fight against infectious
diseases. Since their discovery by Edward Jenner in 1796, vaccines have reduced the …

Alphaviruses are arthropod-transmitted RNA viruses that cause epidemics of human
infection and disease on a global scale. These viruses are classified as either arthritogenic …

Chikungunya virus (CHIKV) is a reemerging mosquito-borne virus that causes swift
outbreaks. Major concerns are the persistent and disabling polyarthralgia in infected …

Background Chikungunya virus (CHIKV) disease is an ongoing public health threat. We
aimed to evaluate the safety and immunogenicity of PXVX0317, an aluminium hydroxide …

Single-stranded RNA viruses such as alphaviruses, flaviviruses, measles viruses and
rhabdoviruses are characterized by their capacity of highly efficient self-amplification of RNA …

Emerging mosquito-borne viruses continue to cause serious health problems and economic
burden among billions of people living in and near the tropical belt of the world. The highly …