Epigenetic protein families: a new frontier for drug discovery
Epigenetic regulation of gene expression is a dynamic and reversible process that
establishes normal cellular phenotypes but also contributes to human diseases. At the …
establishes normal cellular phenotypes but also contributes to human diseases. At the …
NanoGenotoxicology: the DNA damaging potential of engineered nanomaterials
With the rapid expansion in the nanotechnology industry, it is essential that the safety of
engineered nanomaterials and the factors that influence their associated hazards are …
engineered nanomaterials and the factors that influence their associated hazards are …
Lung cancer risk prediction: prostate, lung, colorectal and ovarian cancer screening trial models and validation
CM Tammemagi, PF Pinsky… - Journal of the …, 2011 - academic.oup.com
Introduction Identification of individuals at high risk for lung cancer should be of value to
individuals, patients, clinicians, and researchers. Existing prediction models have only …
individuals, patients, clinicians, and researchers. Existing prediction models have only …
[HTML][HTML] The interplay of arsenic, silymarin, and NF-ĸB pathway in male reproductive toxicity: A review
AG Mukherjee, AV Gopalakrishnan - Ecotoxicology and Environmental …, 2023 - Elsevier
Arsenic toxicity is one of the most trending reasons for several malfunctions, particularly
reproductive toxicity. The exact mechanism of arsenic poisoning is a big question mark …
reproductive toxicity. The exact mechanism of arsenic poisoning is a big question mark …
Cancer epigenetics: a brief review
S Virani, JA Colacino, JH Kim, LS Rozek - ILAR journal, 2012 - academic.oup.com
Cancer is a disease that results from the successive accumulation of genetic and epigenetic
alterations. Despite intense study, many unanswered questions about the nature of the …
alterations. Despite intense study, many unanswered questions about the nature of the …
DNA Methylation Changes in Atypical Adenomatous Hyperplasia, Adenocarcinoma In Situ, and Lung Adenocarcinoma
SA Selamat, JS Galler, AD Joshi, MN Fyfe, M Campan… - PloS one, 2011 - journals.plos.org
Background Aberrant DNA methylation is common in lung adenocarcinoma, but its timing in
the phases of tumor development is largely unknown. Delineating when abnormal DNA …
the phases of tumor development is largely unknown. Delineating when abnormal DNA …
The role of inflammation in the pathogenesis of lung cancer
WCS Cho, CK Kwan, S Yau, PPF So… - Expert opinion on …, 2011 - Taylor & Francis
Introduction: It is reported that cancer may arise in chronically inflamed tissue. There is
mounting evidence suggesting that the connection between inflammation and lung cancer is …
mounting evidence suggesting that the connection between inflammation and lung cancer is …
Role of apoptotic and necrotic cell death under physiologic conditions
SI Han, YS Kim, TH Kim - BMB reports, 2008 - koreascience.kr
Abstract Surgery, Chung-Ang Unviersity College of Medicine, Yong-San Hospital, Seoul,
Korea Apoptosis is considered to be a programmed and controlled mode of cell death …
Korea Apoptosis is considered to be a programmed and controlled mode of cell death …
Cadherin 13 in cancer
AV Andreeva, MA Kutuzov - Genes, Chromosomes and Cancer, 2010 - Wiley Online Library
We review the evidence suggesting the involvement of Cadherin 13 (CDH13, T‐cadherin, H‐
cadherin) in various cancers. CDH13 is an atypical member of the cadherin family, devoid of …
cadherin) in various cancers. CDH13 is an atypical member of the cadherin family, devoid of …
Embedded spheroids as models of the cancer microenvironment
KM Tevis, YL Colson, MW Grinstaff - Advanced biosystems, 2017 - Wiley Online Library
To more accurately study the complex mechanisms behind cancer invasion, progression,
and response to treatment, researchers require models that replicate both the multicellular …
and response to treatment, researchers require models that replicate both the multicellular …