Cell migration and invasiveness significantly contribute to desirable physiological
processes, such as wound healing or embryogenesis, as well as to serious pathological …

Bone is organized in a hierarchical 3D architecture. Traditionally, analysis of the skeletal
system was based on bone mass assessment by radiographic methods or on the …

Over the past two decades, super-resolution microscopy (SRM), which offered a significant
improvement in resolution over conventional light microscopy, has become a powerful tool …

Visualizing biological tissues in vivo at a cellular or subcellular resolution to explore
molecular signaling and cell behaviors is a crucial direction for research into biological …

Autism spectrum disorder (ASD) is identified by a set of neurodevelopmental divergences
that typically affect the social communication domain. ASD is also characterized by …

Polyelectrolyte–protein complexes are widely used to deliver therapeutic proteins. Here, we
present a method for imaging the release of drugs from polyion complex (PIC) micelles in 3D …

Myelination by oligodendrocytes in the central nervous system (CNS) and Schwann cells in
the peripheral nervous system is essential for nervous system function and health. Despite …

We report an optical-based microscopy imaging technology—simultaneous multiple-level
magnification selective plane illumination microscopy (sMx-SPIM) imaging system—that …

Oligodendrocyte progenitor cells (OPCs), also referred to as NG2-glia, are the most
proliferative cell type in the adult central nervous system. While the primary role of OPCs is …

Tuberculosis (TB) preclinical testing relies on in vivo models including the mouse aerosol
challenge model. The only method of determining colony morphometrics of TB infection in a …