[HTML][HTML] Positioning of cellular components by the ParA/MinD family of ATPases

LT Pulianmackal, AG Vecchiarelli - Current Opinion in Microbiology, 2024 - Elsevier
Highlights•The A/D family of ATPases spatially organizes an array of disparate cellular
cargos.•Our understanding of organelle trafficking in bacteria remains in its infancy.•Many …

Dissecting the phase separation and oligomerization activities of the carboxysome positioning protein McdB

JL Basalla, CA Mak, JA Byrne, M Ghalmi, Y Hoang… - Elife, 2023 - elifesciences.org
Across bacteria, protein-based organelles called bacterial microcompartments (BMCs)
encapsulate key enzymes to regulate their activities. The model BMC is the carboxysome …

Multiple ParA/MinD ATPases coordinate the positioning of disparate cargos in a bacterial cell

LT Pulianmackal, JMI Limcaoco, K Ravi, S Yang… - Nature …, 2023 - nature.com
In eukaryotes, linear motor proteins govern intracellular transport and organization. In
bacteria, where linear motors involved in spatial regulation are absent, the ParA/MinD family …

An invariant C-terminal tryptophan in McdB mediates its interaction and positioning function with carboxysomes

JL Basalla, M Ghalmi, Y Hoang, RE Dow… - Molecular Biology of …, 2024 - molbiolcell.org
Bacterial microcompartments (BMCs) are widespread, protein-based organelles that
regulate metabolism. The model for studying BMCs is the carboxysome, which facilitates …

The disordered N-terminus of McdB modulates phase separation via pH-sensitive hydration and folds upon interaction with McdA

JL Basalla, CA Mak, MJ Limcaoco, Y Hoang… - bioRxiv, 2022 - biorxiv.org
Carboxysomes are protein-based organelles essential for efficient CO2-fixation in
cyanobacteria and some chemoautotrophic bacteria. We recently identified the two …

[PDF][PDF] Coordinated Subcellular Organization in Bacteria

S Yang - 2022 - deepblue.lib.umich.edu
Coordinated Subcellular Organization in Bacteria Page 1 Coordinated Subcellular
Organization in Bacteria By Sinyu Yang A thesis submitted in partial fulfillment of the …

ATP-driven Spatial Organization of a Carbon-fixing Organelle in Cyanobacteria

PB Hakim - 2021 - deepblue.lib.umich.edu
Metabolic compartmentalization contributes to the spatiotemporal modulation of biochemical
reactions within eukaryotic and prokaryotic cells. Bacterial microcompartments (BMCs) are …