Biocatalysis making waves in organic chemistry
U Hanefeld, F Hollmann, CE Paul - Chemical Society Reviews, 2022 - pubs.rsc.org
Biocatalysis has an enormous impact on chemical synthesis. The waves in which
biocatalysis has developed, and in doing so changed our perception of what organic …
biocatalysis has developed, and in doing so changed our perception of what organic …
Biocatalytic oxidation reactions: a chemist's perspective
JJ Dong, E Fernández‐Fueyo… - Angewandte Chemie …, 2018 - Wiley Online Library
Oxidation chemistry using enzymes is approaching maturity and practical applicability in
organic synthesis. Oxidoreductases (enzymes catalysing redox reactions) enable chemists …
organic synthesis. Oxidoreductases (enzymes catalysing redox reactions) enable chemists …
Scalable biocatalytic C–H oxyfunctionalization reactions
S Chakrabarty, Y Wang, JC Perkins… - Chemical Society …, 2020 - pubs.rsc.org
Catalytic C–H oxyfunctionalization reactions have garnered significant attention in recent
years with their ability to streamline synthetic routes toward complex molecules …
years with their ability to streamline synthetic routes toward complex molecules …
Hemoprotein catalyzed oxygenations: P450s, UPOs, and progress toward scalable reactions
G Grogan - JACS Au, 2021 - ACS Publications
The selective oxygenation of nonactivated carbon atoms is an ongoing synthetic challenge,
and biocatalysts, particularly hemoprotein oxygenases, continue to be investigated for their …
and biocatalysts, particularly hemoprotein oxygenases, continue to be investigated for their …
Computer-aided tunnel engineering: a promising strategy for improving lipase applications in esterification reactions
W Chong, Y Qi, L Ji, Z Zhang, Z Lu, B Nian, Y Hu - ACS Catalysis, 2023 - ACS Publications
Esterification is one of the most important reactions in organic synthesis and industrial
applications. The applications of lipases in esterification are increasingly widespread and …
applications. The applications of lipases in esterification are increasingly widespread and …
The molecular basis and enzyme engineering strategies for improvement of coupling efficiency in cytochrome P450s
Cytochrome P450s are heme-thiolate enzymes that have been broadly applied in
pharmaceutical and biosynthesis because of their efficient oxidation at inert carbons …
pharmaceutical and biosynthesis because of their efficient oxidation at inert carbons …
Biokatalytische Oxidationsreaktionen–aus der Sicht eines Chemikers
JJ Dong, E Fernández‐Fueyo, F Hollmann… - Angewandte …, 2018 - Wiley Online Library
Enzyme gewinnen immer mehr Bedeutung als Katalysatoren für organische
Oxidationsreaktionen. Mit Oxidoreduktasen stehen dem Chemiker vielseitige Werkzeuge für …
Oxidationsreaktionen. Mit Oxidoreduktasen stehen dem Chemiker vielseitige Werkzeuge für …
Choose Your Own Adventure: A Comprehensive Database of Reactions Catalyzed by Cytochrome P450 BM3 Variants
DJ Fansher, JN Besna, A Fendri, JN Pelletier - ACS catalysis, 2024 - ACS Publications
Cytochrome P450 BM3 monooxygenase is the topic of extensive research as many
researchers have evolved this enzyme to generate a variety of products. However, the …
researchers have evolved this enzyme to generate a variety of products. However, the …
MicroGelzymes: pH-independent immobilization of cytochrome P450 BM3 in microgels
M Nöth, L Hussmann, T Belthle, I El-Awaad… - …, 2020 - ACS Publications
Microgels are an emerging class of “ideal” enzyme carriers because of their chemical and
process stability, biocompatibility, and high enzyme loading capability. In this work, we …
process stability, biocompatibility, and high enzyme loading capability. In this work, we …
Engineering metalloprotein functions in designed and native scaffolds
Metalloproteins are crucial for life. The mutual relationship between metal ions and proteins
makes metalloproteins able to accomplish key processes in biological systems, often very …
makes metalloproteins able to accomplish key processes in biological systems, often very …