Malaria poses a severe public health risk and a significant economic burden in disease-
endemic countries. One of the most severe issues in malaria control is the development of …

Pyrazolines are five-membered heterocycles possessing two adjacent nitrogens. They have
attracted significant attention from organic and medicinal chemists due to their potent …

Pyrazolines remain privileged heterocycles in drug discovery. 2-Pyrazoline scaffold has
been proven as a ubiquitous motif which is present in a number of pharmacologically …

In this study, an efficient synthesis of new thiazole-pyrazoline hybrids was investigated and
hybrids were screened for their antimicrobial activities against four species of pathogenic …

The design and synthesis of novel fluorescent heterocyclic dyes is a “hotspot” research area,
due to their favourable photophysical properties and crucial role in charge transfer …

A novel series of pyrazolyl chalcones containing quinoline scaffold, 5 av has been
synthesized by Claisen Schimdt condensation of aromatic acetophenone with 1-(4 …

Malaria has been a major parasitic disease in tropical and subtropical regions and is
estimated to kill between one and two million people (mainly children) every year. Novel anti …

Pyrazolines and pyrazolones are prevalent cores in drugs and bioactive molecules.
Functionalizing them with heteroatoms on the ring improves or expands their clinical …

It has been established that pyrazolines and their analogs are pharmacologically active
scaffolds. The pyrazoline moiety is present in several marketed molecules with a wide range …

A series of nine new complexes of ruthenium (II), rhodium (III), and iridium (III) incorporated
with pyrazoline-based ligands were synthesized and characterized by various spectroscopic …