Approaches to surface engineering of extracellular vesicles
M Richter, P Vader, G Fuhrmann - Advanced drug delivery reviews, 2021 - Elsevier
Extracellular vesicles (EVs) are cell-derived nanoparticles that are important mediators in
intercellular communication. This function makes them auspicious candidates for therapeutic …
intercellular communication. This function makes them auspicious candidates for therapeutic …
Designer outer membrane vesicles as immunomodulatory systems–reprogramming bacteria for vaccine delivery
YMD Gnopo, HC Watkins, TC Stevenson… - Advanced Drug Delivery …, 2017 - Elsevier
Vaccines often require adjuvants to be effective. Traditional adjuvants, like alum, activate the
immune response but in an uncontrolled way. Newer adjuvants help to direct the immune …
immune response but in an uncontrolled way. Newer adjuvants help to direct the immune …
Delivery of toxins and effectors by bacterial membrane vesicles
A Macion, A Wyszyńska, R Godlewska - Toxins, 2021 - mdpi.com
Pathogenic bacteria interact with cells of their host via many factors. The surface
components, ie, adhesins, lipoproteins, LPS and glycoconjugates, are particularly important …
components, ie, adhesins, lipoproteins, LPS and glycoconjugates, are particularly important …
Biosynthetically engineered lipopolysaccharide as vaccine adjuvant
A Zariri, P van der Ley - Expert review of vaccines, 2015 - Taylor & Francis
Lipopolysaccharide (LPS), a dominant component of the Gram-negative bacterial outer
membrane, is a strong activator of the innate immune system, and thereby an important …
membrane, is a strong activator of the innate immune system, and thereby an important …
Development of Different Methods for Preparing Acinetobacter baumannii Outer Membrane Vesicles Vaccine: Impact of Preparation Method on Protective Efficacy
S Li, DQ Chen, L Ji, S Sun, Z Jin, ZL Jin… - Frontiers in …, 2020 - frontiersin.org
Acinetobacter baumannii (A. baumannii) is becoming a common global concern due to the
emergence of multi-drug or pan-drug resistant strains. Confronting the issue of antimicrobial …
emergence of multi-drug or pan-drug resistant strains. Confronting the issue of antimicrobial …
[HTML][HTML] A bacterial vesicle-based pneumococcal vaccine against influenza-mediated secondary Streptococcus pneumoniae pulmonary infection
Streptococcus pneumoniae (Spn) is a common pathogen causing a secondary bacterial
infection following influenza, which leads to severe morbidity and mortality during seasonal …
infection following influenza, which leads to severe morbidity and mortality during seasonal …
Flagellin-deficient outer membrane vesicles as adjuvant induce cross-protection of Salmonella Typhimurium outer membrane proteins against infection by …
Q Liu, K Tan, J Yuan, K Song, R Li, X Huang… - International journal of …, 2018 - Elsevier
Salmonella enteric serovar infections result in high morbidity and mortality worldwide. Cross-
protective vaccines are an effective strategy in controlling salmonellosis caused by multiple …
protective vaccines are an effective strategy in controlling salmonellosis caused by multiple …
Outer Membrane Vesicles from Neisseria Meningitidis (Proteossome) Used for Nanostructured Zika Virus Vaccine Production
The increase of Zika virus (ZIKV) infections in Brazil in the last two years leaves a
prophylactic measures on alert for this new and emerging pathogen. Concerning of our …
prophylactic measures on alert for this new and emerging pathogen. Concerning of our …
Pneumonic Plague Protection Induced by a Monophosphoryl Lipid A Decorated Yersinia Outer‐Membrane‐Vesicle Vaccine
S Majumder, S Das, P Li, N Yang, H Dellario, H Sui… - Small, 2024 - Wiley Online Library
A new Yersinia pseudotuberculosis mutant strain, YptbS46, carrying the lpxE insertion and
pmrF‐J deletion is constructed and shown to exclusively produce monophosphoryl lipid A …
pmrF‐J deletion is constructed and shown to exclusively produce monophosphoryl lipid A …
[HTML][HTML] Variability of in vivo potency assays of whole-cell pertussis, inactivated polio, and meningococcal B vaccines
C van Walstijn, S Verweij, R Care, P Rigsby… - Vaccine, 2023 - Elsevier
For the batch release of vaccines, potency release assays are required. Non-animal in vitro
tests have numerous advantages and are preferred; however, several vaccines are still …
tests have numerous advantages and are preferred; however, several vaccines are still …