Background An assessment of the correlation between anti-malarial treatment outcome and
molecular markers would improve the early detection and monitoring of drug resistance by …

This review article aims to investigate the genotypic profiles of Plasmodium falciparum and
Plasmodium vivax isolates collected across a wide geographic region and their association …

Adequate clinical and parasitologic cure by artemisinin combination therapies relies on the
artemisinin component and the partner drug. Polymorphisms in the Plasmodium falciparum …

We assessed Plasmodium falciparum mdr1 (Pf mdr1) gene polymorphisms and copy
numbers as well as P. falciparum Ca2+ ATPase (Pf ATPase6) gene polymorphisms in 90 …

Malaria affects 200 million people worldwide. Today, the most successful treatments are
artemisinin-based combination therapies (ACT). Resistance has already been described for …

Despite the pharmacodynamic advantages with artemisinin-based combination therapy
(ACT) and some potentially opposite molecular mechanisms of tolerance to amodiaquine …

ABSTRACT The involvement of Pfmdr1 (Plasmodium falciparum multidrug resistance 1)
polymorphisms in antimalarial drug resistance is still debated. Here, we evaluate the …

ABSTRACT Artemether-lumefantrine (AL), dihydroartemisinin-piperaquine (DP), and
amodiaquine-sulfadoxine-pyrimethamine (AQ-SP) offer excellent antimalarial efficacy but …

Objective To investigate the antimalarial potential of kolaviron (KV), a biflavonoid fraction
from Garcinia kola seeds, against Plasmodium berghei (P. berghei) infection in Swiss albino …

Malaria is an endemic disease, prevalent in tropical and subtropical regions which cost half
of million deaths annually. The eradication of malaria is one of the global health priority …