Primary CNS lymphoma (PCNSL) is a rare form of extranodal non-Hodgkin lymphoma that is
typically confined to the brain, eyes, and cerebrospinal fluid without evidence of systemic …

Important advances have been made in the understanding and management of adult
gliomas and primary CNS lymphomas—the two most common primary brain tumours …

Background Chemotherapy with high-dose methotrexate is the conventional approach to
treat primary CNS lymphomas, but superiority of polychemotherapy compared with high …

Primary central nervous system lymphoma (PCNSL) is a rare form of non-Hodgkin
lymphoma that affects the brain parenchyma, spinal cord, eyes, and cerebrospinal fluid …

Primary central nervous system lymphoma (PCNSL) is a rare and aggressive extranodal
non‐Hodgkin lymphoma (NHL) that is confined to the brain, eyes, spinal cord, or …

Primary CNS lymphoma (PCNSL) is a rare lymphoma that is confined to the CNS, with low
tendency for systemic dissemination and a relatively aggressive course. Outcome in patients …

Primary CNS lymphoma (PCNSL) is a rare malignancy with peculiar clinical and biologic
features, aggressive course, and unsatisfactory outcome. It represents a challenge for …

The pathogenesis of primary and secondary central nervous system (CNS) lymphoma poses
a unique set of diagnostic, prognostic, and therapeutic challenges. During the past 10 years …

Purpose In this phase II study (NCT00942747), temsirolimus was tested in patients with
relapsed or refractory primary CNS lymphoma (PCNSL). Patients and Methods …

Recent studies addressing the molecular characteristics of PCNSL, which is defined as
malignant B-cell lymphoma with morphological features of DLBCL, have significantly …