Long non-coding RNAs and cancer: a new frontier of translational research?

R Spizzo, MI Almeida, A Colombatti, GA Calin - Oncogene, 2012 - nature.com
Tiling array and novel sequencing technologies have made available the transcription
profile of the entire human genome. However, the extent of transcription and the function of …

Long noncoding RNAs as novel biomarkers have a promising future in cancer diagnostics

T Shi, G Gao, Y Cao - Disease markers, 2016 - Wiley Online Library
Cancers have a high mortality rate due to lack of suitable specific early diagnosis tumor
biomarkers. Emerging evidence is accumulating that lncRNAs (long noncoding RNAs) are …

Increased expression of lncRNA CASC9 promotes tumor progression by suppressing autophagy-mediated cell apoptosis via the AKT/mTOR pathway in oral …

Y Yang, D Chen, H Liu, K Yang - Cell Death & Disease, 2019 - nature.com
Recent studies showed that lncRNA CASC9 was upregulated and acted as an oncogene in
a variety of tumors. However, the expression and biological functions of CASC9 in oral …

LncRNA IFITM4P promotes immune escape by up-regulating PD-L1 via dual mechanism in oral carcinogenesis

L Shi, Y Yang, M Li, C Li, Z Zhou, G Tang, L Wu, Y Yao… - Molecular Therapy, 2022 - cell.com
Oral squamous cell carcinoma (OSCC), which is typically preceded by oral leukoplakia (OL),
is a common malignancy with poor prognosis. However, the signaling molecules governing …

Salivary lncRNA as a potential marker for oral squamous cell carcinoma diagnosis

H Tang, Z Wu, J Zhang, B Su - Molecular medicine …, 2013 - spandidos-publications.com
Oral squamous cell carcinoma (OSCC) is a common and lethal malignancy. Thus,
improvement in current knowledge of molecular changes associated with OSCC is urgently …

Long non-coding RNAs: challenges for diagnosis and therapies

Y Sánchez, M Huarte - Nucleic acid therapeutics, 2013 - liebertpub.com
Long non-coding RNAs (lncRNAs) have emerged as one of the largest and more diverse
classes of cellular transcripts. The growing evidence suggests that lncRNAs are key …

Long noncoding RNAs as new architects in cancer epigenetics, prognostic biomarkers, and potential therapeutic targets

D Meseure, K Drak Alsibai, A Nicolas… - BioMed research …, 2015 - Wiley Online Library
Recent advances in genome‐wide analysis have revealed that 66% of the genome is
actively transcribed into noncoding RNAs (ncRNAs) while less than 2% of the sequences …

[HTML][HTML] Long non-coding RNAs in colorectal cancer

X Xie, B Tang, YF Xiao, R Xie, BS Li, H Dong, JY Zhou… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is one of the leading causes of cancer-related death worldwide.
Despite substantial progress in understanding the molecular mechanisms and treatment of …

Increased expression of the long non-coding RNA UCA1 in tongue squamous cell carcinomas: a possible correlation with cancer metastasis

Z Fang, L Wu, L Wang, Y Yang, Y Meng… - Oral surgery, oral …, 2014 - Elsevier
Objective The aim of this study was to examine the expression of several cancer-related
long non-coding RNAs (lncRNAs) in patients with tongue squamous cell carcinoma (TSCC) …

Influence of microRNAs and long non-coding RNAs in cancer chemoresistance

D Ayers, J Vandesompele - Genes, 2017 - mdpi.com
Innate and acquired chemoresistance exhibited by most tumours exposed to conventional
chemotherapeutic agents account for the majority of relapse cases in cancer patients. Such …