Major depressive disorder (MDD) is a debilitating illness characterized by neuroanatomical
and functional alterations in limbic structures, notably the prefrontal cortex (PFC), that can be …

GABAB receptors are broadly expressed in the nervous system and have been implicated in
a wide variety of neurological and psychiatric disorders. The cloning of the first GABAB …

The γ-aminobutyric acidB (GABAB) receptor was first demonstrated on presynaptic terminals
where it serves as an autoreceptor and also as a heteroreceptor to influence transmitter …

Abstract γ-aminobutyric acid type B (GABA B) receptors are broadly expressed in the
nervous system and play an important role in neuronal excitability. GABA B receptors are G …

Brain‐derived neurotrophic factor (BDNF) is a member of the neurotrophin family that plays
a critical role in numerous neuronal activities. Recent studies have indicated that some …

Brain-derived neurotrophic factor (BDNF) belongs to the neurotrophin family which interacts
with high-affinity protein kinase receptors (Trk) and the unselective p75NGFR receptor. The …

Major depression is a debilitating and recurrent disorder with a substantial lifetime risk and a
high social cost. Depressed patients generally display co-morbid symptoms, and depression …

GABA, the main inhibitory neurotransmitter in the brain, regulates many physiological and
psychological processes. Thus, dysfunction of the GABA system is implicated in the …

Adaptation of the nervous system to different chemical and physiologic conditions is
important for the homeostasis of brain processes and for learning and remembering …

Central regulation of metabolic physiology is mediated critically through neuronal functions;
however, whether astrocytes are also essential remains unclear. Here we show that the high …