Introduction: Discovery proteomics for cancer research generates complex datasets of
diagnostic, prognostic, and therapeutic significance in human cancer. With the advent of …

It is still a question of debate whether neutrophils, often found in the tumor
microenvironment, mediate tumor-promoting or rather tumor-inhibiting activities. The present …

Clinical management of melanomas with NRAS mutations is challenging. Targeting MAPK
signaling is only beneficial to a small subset of patients due to resistance that arises through …

The MM500 meta‐study aims to establish a knowledge basis of the tumor proteome to serve
as a complement to genome and transcriptome studies. Somatic mutations and their effect …

Purpose: Despite high clinical need, there are no biomarkers that accurately predict the
response of patients with metastatic melanoma to anti-PD-1 therapy. Experimental Design …

Cell invasion is an initiating event during tumor cell metastasis and an essential process
during development. A screen of C. elegans orthologs of genes overexpressed in invasive …

Overdiagnosis of early melanoma is a significant problem. Due to subtle unique and
overlapping clinical and histological criteria between pigmented lesions and the risk of …

Octenidine dihydrochloride (OCT) is a widely used antiseptic molecule, promoting skin
wound healing accompanied with improved scar quality after surgical procedures. However …

Despite recent developments in managing metastatic melanomas, patients' overall survival
remains low. Therefore, the current study aims to understand better the proteome‐wide …

Introduction The implications of infiltrative compared to non‐infiltrative growth of cutaneous
basal cell carcinoma (BCC) on the tumor stroma and immune cell landscape are unknown …