Transcripts and/or proteins of P2X receptor (P2XR) subunits have been found in virtually all
mammalian tissues. Generally more than one of the seven known P2X subunits have been …

Chronic pain is a common symptom of most clinical diseases, which seriously affects the
psychosomatic health of patients and brings some pain to patients. Due to its pathological …

Neuropathic pain (NPP) is a common symptom of most diseases in clinic, which seriously
affects the mental health of patients and brings certain pain to patients. Due to its …

The blockade or deletion of the pro-inflammatory P2X7 receptor channel has been shown to
reduce tissue damage and symptoms in models of inflammatory bowel disease, and P2X7 …

Abstract Purinergic Signalling in the Enteric Nervous System involves the regulated release
of ATP (or a structurally-related nucleotide) which activates an extensive suite of membrane …

The main pathological features of ischemic stroke include neuronal damage and blood–
brain barrier (BBB) dysfunction. Previous studies have shown that Evans Blue, a dye used to …

Aim Our earlier studies showed that mechanical stretch activates inhibitory motor neurons of
the oesophagus; however, the underlying molecular mechanisms are unclear. Here, we …

P2X 3 receptor expression in various tissues appears to be modulated by age. In the present
study, we used single cell RT-PCR to determine the number of P2X 3 positive myenteric …

Gene coding for ATP-gated receptor ion channels (P2X1–7) has been associated with the
developmental process in various tissues; among these ion channel subtypes, P2X6 acts as …

Se ha reportado que la inflamación intestinal de bajo grado inducida por una dieta rica en
grasas detona la inflamación sistémica crónica, que es un sello distintivo de la obesidad, y …