The gem-difluoroalkenes and related compounds have gained much attention from the
organic synthetic community due to their widespread applications as versatile fluorinated …

Abstract gem‐Heteroatom‐substituted fluoroalkenes have received little attention despite
their great potential in medicinal chemistry or in fine chemistry. Indeed, due to the electronic …

A photocatalytic decarboxylative/defluorinative reaction of α-trifluoromethyl alkenes with α-
keto acids and α-amino acids has been developed. The reaction occurs at room temperature …

A visible-light-promoted redox neutral γ, γ-difluoroallylation of cycloketone oxime ethers with
trifluoromethyl alkenes through C–C and C–F bond cleavage has been achieved, which …

Fluoroindoles as an important structural scaffold are widely existing in many bioactive or
therapeutic agents. Despite their potential usefulness, efficient constructions of 2 …

Monofluoroalkenes have found wide application in organic chemistry, medicinal chemistry,
and materials science. This review summarizes the most recent advances made regarding …

gem-Difluoroalkene bearing a carbonyl group is a challenging target to synthesize by
conventional methods. Herein we report a mild and concise route to access the target …

A mild and versatile method for the construction of C–N bonds by the reaction of (2, 2-
difluorovinyl) arenes with various N–H-containing heterocycles in the presence of K3PO4 …

The construction of ring-fluorinated seven-membered carbocycles was readily achieved via
the domino SN2′-type/SNV reaction between 2-(trifluoromethyl)-1-alkenes and 1, 4 …

The treatment of CF3-bearing cyclopropanes with Et2AlCl generated stabilized
difluorocarbocations, which underwent a nucleophilic addition of thiocarboxylic acids or …