The discovery of Asgard archaea, phylogenetically closer to eukaryotes than other archaea,
together with improved knowledge of microbial ecology, impose new constraints on …

LTR retrotransposons are the most abundant group of transposable elements (TEs) in
plants. These elements can fall inside or close to genes, and therefore influence their …

The duality of group II introns, capable of carrying out both self-splicing and retromobility
reactions, is hypothesized to have played a profound role in the evolution of eukaryotes …

During the evolution of eukaryotic genomes, many genes have been interrupted by
intervening sequences (introns) that must be removed post-transcriptionally from RNA …

The emergence of introns was a significant evolutionary leap that is a major distinguishing
feature between prokaryotic and eukaryotic genomes. While historically introns were …

In this feature article, we provide a side-by-side introduction for two research fields: quantum
chemical calculations of molecular interaction in nucleic acids and RNA structural …

The spliceosome is a eukaryote-specific complex that is essential for the removal of introns
from pre-mRNA. It consists of five small nuclear RNAs (snRNAs) and over a hundred …

We review the introns-first hypothesis a decade after it was first proposed. It is that exons
emerged from non-coding regions interspersed between RNA genes in an early RNA world …

Intron number varies considerably among genomes, but despite their fundamental
importance, the mutational mechanisms and evolutionary processes underlying the …

Introns inserted within introns are commonly referred to as twintrons, however the original
definition for twintron implied that splicing of the external member of the twintron could only …